Histology Flashcards
What epithelium lines the oral cavity and pharynx?
stratified squamous epithelium
non-keratinizing
define parakeratinized
not truely karatinized
What 2 types of epithelial cells are present in the oral cavity?
Describe both of them
masticatory epithlium (hard palate, dorsum of tongue) - usually parakeratinized, whitish
lining epithelium - non-keratinized, pinkish
what are the 3 layers of the mucosa of the oral cavity?
epithlium
lamina propria
muscle/bone
What’s the most common type of cancer in the mouth? 3 types of cancers of the oral cavity
squamous cell carcinoma (tongue and floor)
- malignant melanomas
- adenocarcinomas (hard palate)
3 layers of the skin on the lips?
What are the epithelia type of each?
skin-keratinized squamous w/ adenxal structures
free margin - keratinized squamous w/o adenxal structures
mucosa - non/para-kertanized squamous
on the tongue: what’s the epithelium of the lateral surface, anterior dorsal, and posterior dorsal surface?
lateral - lining epithelium
anterior - masticatory w/ papillae
posterior - lining
What does the posterior 1/3rd of the tongue contain?
What does the anterior 2/3rd contain?
1/3 = lingual tonsil 2/3 = papillae
What are the 4 types of papillae?
Which ones are ubiquitous? Which ones have taste buds?
For the circumscript, where are they located?
filiform - ubiquitous
fungiform - ubiquitous
circumvallate - on terminal sulcus
foliate - on dorsolateral
T/F Taste buds are in direct contact with the contents of the mouth at all times
False - selective barrier
What’s the opening from taste bud to the mouth?
What are the projections through the ^ called?
How many taste receptor cells to one taste bud?
via taste pore
microvilli
50-100 cells = taste bud
what are the 4 types of cells for taste buds?
Ion channels – what are the 2 types?
G-Protein – what are the 2 types.
I - supporting
II - receptor
III - presynaptic
IV - stem
- ion channels: TRP or ENaC
- G-protein: type I/II
How many taste receptor cells are there? Go through them in detail. What do they taste?
3 cell types with 4 taste receptors
Type I - ENaC receptor salty
II - T1R/T2R receptor - umami, sweet, bitter
III- TRP receptor - sour
Explain the neuronal pathway of taste. How many nerves? Where do they all go to?
What are the 3 ganglia?
projections from cell bodies in three different ganglia that mostly travel with other CN
travel to primary cortex
-nodose (w/ vagus n)
-inferior glossopharyngeal ganglion (w/glossopharyngeal)
geniculate ganglion (w/facial nerve)
what are the 3 major salivary glands? Which ones are capsulated, and which ones are outside the oral cavity?
sublingual - NON-capsulated
submandibular - capsulated
parotid = capsulated
both capsulated outside outside oral cavity
of the salivary gland structure
What divides the glands?
What are the 2 functional parts and what do they do?
septa
acini = produce saliva duct = modify and transport
what are the 2 types of secretions form the glands?
From acinus, what are the 2 ducts that follow?
watery or slimy
intercalated duct then striated duct
what is the epithelium progression from**
Intercalated ducts to striated ducts
From striated ducts to interlobular ducts
What are the secretory portions, and what are the excretory portions?
squamous to cuboidal
cuboidal to columnar
stratified cuboidal to columnar
interlobular = excretory
what are myoepithelial cells? Describe them. How would you identify them histologically?
spider-like contractile cells
mediate expulsion of saliva
What 2 types of Ig are made in the oral cavity? What’s the third one that’s also found and why?
Which Ig can’t pass through to the oral cavity and stays in the interstitium?
IgA and IgM
IgG due to paracellular leakage
IgM can’t pass
Of the major salivary glands, which ones secrete mostly what?
How do you distinguish between serous or mucous glands?
parotid- serous
submandibular - muco-serous
sublingual - sero-mucous
what place contains loads of minor salivary glands?
hard palate and tongue
