Histology Flashcards
What epithelium lines the oral cavity and pharynx?
stratified squamous epithelium
non-keratinizing
define parakeratinized
not truely karatinized
What 2 types of epithelial cells are present in the oral cavity?
Describe both of them
masticatory epithlium (hard palate, dorsum of tongue) - usually parakeratinized, whitish
lining epithelium - non-keratinized, pinkish
what are the 3 layers of the mucosa of the oral cavity?
epithlium
lamina propria
muscle/bone
What’s the most common type of cancer in the mouth? 3 types of cancers of the oral cavity
squamous cell carcinoma (tongue and floor)
- malignant melanomas
- adenocarcinomas (hard palate)
3 layers of the skin on the lips?
What are the epithelia type of each?
skin-keratinized squamous w/ adenxal structures
free margin - keratinized squamous w/o adenxal structures
mucosa - non/para-kertanized squamous
on the tongue: what’s the epithelium of the lateral surface, anterior dorsal, and posterior dorsal surface?
lateral - lining epithelium
anterior - masticatory w/ papillae
posterior - lining
What does the posterior 1/3rd of the tongue contain?
What does the anterior 2/3rd contain?
1/3 = lingual tonsil 2/3 = papillae
What are the 4 types of papillae?
Which ones are ubiquitous? Which ones have taste buds?
For the circumscript, where are they located?
filiform - ubiquitous
fungiform - ubiquitous
circumvallate - on terminal sulcus
foliate - on dorsolateral
T/F Taste buds are in direct contact with the contents of the mouth at all times
False - selective barrier
What’s the opening from taste bud to the mouth?
What are the projections through the ^ called?
How many taste receptor cells to one taste bud?
via taste pore
microvilli
50-100 cells = taste bud
what are the 4 types of cells for taste buds?
Ion channels – what are the 2 types?
G-Protein – what are the 2 types.
I - supporting
II - receptor
III - presynaptic
IV - stem
- ion channels: TRP or ENaC
- G-protein: type I/II
How many taste receptor cells are there? Go through them in detail. What do they taste?
3 cell types with 4 taste receptors
Type I - ENaC receptor salty
II - T1R/T2R receptor - umami, sweet, bitter
III- TRP receptor - sour
Explain the neuronal pathway of taste. How many nerves? Where do they all go to?
What are the 3 ganglia?
projections from cell bodies in three different ganglia that mostly travel with other CN
travel to primary cortex
-nodose (w/ vagus n)
-inferior glossopharyngeal ganglion (w/glossopharyngeal)
geniculate ganglion (w/facial nerve)
what are the 3 major salivary glands? Which ones are capsulated, and which ones are outside the oral cavity?
sublingual - NON-capsulated
submandibular - capsulated
parotid = capsulated
both capsulated outside outside oral cavity
