Human disease Flashcards
What are the 5 acute or chronic features of inflammation?
Redness
Heat
Pain
Swelling
Loss of function
What are the 2 stages of acute inflammation?
Vascular response
Cellular response
What is vascular response?
Blood vessels dilate blood flow slows
What is cellular response?
Attracts white blood cells to the area
Functions of fluid exudate?
Carries substances
Dilutes irritant substances
Carries fibrinogen from blood to tissues
What does fibrin do?
Localises irritant
Helps phagocytosis
What are the 2 results of acute inflammation?
Resolution - when there is little tissue damage
Suppuration- too much tissue damage, pus formation and irreversible
What does pus contain?
Necrotic tissue/dead cells
•Fibrin
•Micro-organisms
•Tissue debris
•Tissue fluid
What are the 3 phases of response to injury?
Acute inflammation
Demolitions
Healing
3 Features of chronic inflammation
Active inflammation
Fluid
Demolition
Chronic inflammation healing depends on what factors?
Depends on amount of damage to tissue
Key feature is formation of granulation tissue
What is granulation tissue?
New connective tissues which forms during the healing process
What does granulation tissue contain?
Endothelial cells forming blood and lymphatic vessels.
●Fibroblasts forming collagen.
●Lymphocytes and plasma cells.
●Fibroblasts may lay down excessive amounts of collagen, this is non-functional ——->gingival hyperplasia.
The triple response can be produced by ————, which is probably released by ———-
Histamine
Mast cells
