HTN, PVD, PAD Flashcards
The largest artery in the body
Aortic artery
Factors that affect blood pressure
Peripheral resistance, vessel elasticity, blood volume, cardiac output
The volume of blood pumped by each side (ventricle) of the heart in one minute
Cardiac output
Resistance of blood vessels to blood flow
Peripheral resistance
The total amount of blood in the circulatory system
Blood volume
Components of the blood
Nutrients and oxygen
Decreased blood volume causes __________, while elevated blood volume causes _________
Dehydration & hypotension; hypertension
Peripheral vascular disease (PVD) most commonly affects the
Extremities; particularly the lower extremities
Volume of blood pumped by each ventricle in one contraction (heartbeat)
Stroke volume (SV)
How much blood is pumped out of the left ventricle with each heartbeat?
~ 70 mL
Typical heart rate
75 bpm
Ways to increase cardiac output
Increase SV, increase HR, or increase both
Cardiac output equation
CO = SV x HR
Blood pressure equation
Blood pressure (P) = Cardiac output (Q) x vascular resistance (R)
Which two factors are interconnected through the hemodynamic regulation of blood pressure?
Cardiac output and hypertension
Hypertension that is developed over time
Primary or essential
Risk factors for primary/essential hypertension
Genetics, smoking, obesity, high salt intake, high alcohol consumption, stress, lack of exercise, aging
Hypertension that occurs quickly and more severely
Secondary
risk factors for secondary hypertension
Obstructive sleep apnea, heart defects, kidney disease, medications or illegal drugs, adrenal/thyroid conditions
Hormone that is released when the body senses that BP and/or blood volume is low
Renin
Renin triggers
Angiotensin
Angiotensin signals __________ to retain sodium and water when BP is low, or release sodium and water when BP is high
Aldosterone
Electrolyte imbalance associated with ACE inhibitors
Hyperkalemia (release of sodium and water, retention of potassium)
Cardiac complications of HTN
Coronary artery disease —> angina or MI, left ventricular hypertrophy, HF
Brain complications of HTN
TIA, stroke, cognitive impairment, vascular dementia
Kidney complications of HTN
Chronic kidney disease (CKD), end-stage renal disease (ESRD)
Eye complications of HTN
Hypertensive retinopathy —> damage to retinal blood vessels, vision impairment, blindness
Blood vessel complications of HTN
Atherosclerosis, PAD, increased risk of aneurysms and vascular complications
Nervous system complications of HTN
Peripheral neuropathy (particularly in individuals with poorly controlled HTN)
Atherosclerosis/PVD/PAD risk factors
Aging, genetics, gender, hyperlipidemia, HTN, smoking, DM, lack of exercise, stress, obesity
Chronic inflammatory disorder that causes build up of cholesterol plaques on medium and large arteries
Atherosclerosis
Loss of arterial elasticity through the hardening and thickening of arterial walls
Arteriosclerosis
Most common cause of PAD
Atherosclerosis
Most common arteries affected by atherosclerosis
Abdominal aorta, coronary, popliteal, carotid
PAD pathophysiology
Hardening of fatty deposits in arteries narrow the opening and block effective blood flow
An umbrella term for disorders affecting blood vessels outside the heart and brain
Peripheral vascular disease (PVD)
A specific type of PVD where plaque buildup occurs in arteries carrying blood to extremities, especially the legs
Peripheral artery disease (PAD)