HTN Day 2 Flashcards
Which beta blockers are cardioselective?
AMEBBA
Atenolol, Metoprolol, Esmolol, Bisprolol, Betaxalol, Acebutolol
What are the ADEs of beta blockers?
“Beta blocker blues” = tired, depressed, sexual dysfunction
Which ADEs of beta blockers will resolve with time and which will not?
- Fatigue/depression should resolve with time
- Sexual dysfunction will not resolve with time
What happens when beta blocker doses are skipped or the drug is stopped suddenly?
Rebound HTN
How are beta blockers used for HTN?
They are NOT 1st line
Reserved for patients with cardiac history (MI, HF, CAD)
What are the major CIs to beta blockers?
Asthma/COPD - use selective agents only
DM - masks hypoglycemia symptoms (except sweating!)
What should DM patients on beta blockers be aware of?
B blockers mask the symptoms of hypoglycemia EXCEPT sweating
Unique feature(s) of sotalol
- Beta blocker but NOT used for HTN
- Only used as an anti-arrhythmic agent
What are the mixed alpha and beta blockers?
Carvedilol
Labetalol
Which beta blocker is safe for use in pregnancy?
Labetalol
Which beta blockers have ISA?
CAPP
Carteolol, Acebutolol, Penbutolol, Pindolol
Which beta blockers have non-specific activity?
Nadolol, propranolol, timolol
Features of propranolol
- Migraine prophylaxis (lipophilic, can cross BBB)
- Used for tx of “stage fright” anxiety
What are examples of alpha 1 blockers?
Prazosin, doxazosin, tamsulosin, alfuzosin
MOA of alpha 1 blockers
- Inhibits peripheral alpha-1 receptors
- Causes vasodilation
