HPV Vaccine Flashcards
1
Q
What strains of HPV virus cause genital warts on the skin around the anus and vagina?
A
HPV 6
HPV 11
2
Q
What strains of HPV cause cells in the throat or cervix to undergo dysplasia?
A
HPV 16
HPV 18
3
Q
What type of vaccine is HPV?
A
Subunit
4
Q
Why is a superior immune response created against the HPV vaccine rather than wild type virus?
A
HPV vaccine rarely exposes the virus to the immune system
Free virus particles are released from the surface of squamous epithelial cells with little viraemia or virus entering the lymphatic system
IM injection with HPV vaccine readily leads to virus proteins being taken up by cDCs and the rapid carriage of virus protein by the DC to the draining lymph node to trigger an adaptive immune response
