How Genes Work Flashcards

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1
Q

Null

A

Alleles that do not function.

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2
Q

Genetic Screen

A

Any technique for picking a particular type of mutants out of randomly generated mutants.

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3
Q

Proteins

A

The workers of cells, functioning enzymes, motors, structural elements, transporters, signals, and regulators.

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4
Q

Transcription

A

The process of using a DNA template to make an RNA molecule that has a base sequence complementary to the DNA.

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5
Q

Translation

A

The process of using the information in mRNA to synthesize proteins.

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6
Q

Reverse Transcriptase

A

An enzyme that can synthesize DNA from an RNA template.

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7
Q

Genetic Code

A

The rules that specify the relationship between a sequence of nucleotides in DNA or RNA and the sequence of amino acids in a protein.

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8
Q

Codon

A

A group of 3 bases that specifies a particular amino acid.

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9
Q

Reading Frame

A

A series of adjacent non-overlapping, 3 base long sequences in DNA or RNA.

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10
Q

Point Mutation

A

Mutation that alters the sequence of one or a small number of base pairs.

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11
Q

Missense Mutations

A

Point mutation that change the identity of an amino acid in a protein.

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12
Q

Silent Mutation

A

Point mutation that does not change the amino acid sequence of the gene product.

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13
Q

Frameshift Mutation

A

Point mutation with addition or deletion of a single base pair that shifts the reading frame.

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14
Q

Nonsense Mutation

A

Point mutation that occurs when a codon that specifies an amino acid is changed by the mutation to one that specifies a stop codon.

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15
Q

Polyploidy

A

State of having more than two of each chromosome.

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16
Q

Aneuploidy

A

Results in the addition and deletion of individual chromosomes.

17
Q

Inversion

A

Segments of a chromosome that may be flipped or rejoined.

18
Q

Translocation

A

Segments that are attached to a different chromosome.

19
Q

Karyotype

A

The complete set of chromosomes in a cell or a cancerous human cell.