How are enzymes classified? Flashcards

1
Q

How are enzymes named

A

Take the substrate and add the suffix “ase”

Prote ase

Amyl ase

Lip ase

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2
Q

What are 2 other examples of older names which give no clue to the substrate they catalyse

A
  • Trypsin
  • Pepson
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3
Q

How might enzymes be classified

A
  • According to the type of reaction they catalyse
    • e.g. Alcohol dehydrogenase removes hydrogen from alcohol
  • Another example is
    • DNA polymerase catlyses the formation and break down of DNA by polymerisations
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4
Q

What are the 6 mains groups of enzymes classified by the nature of their actions

A
  1. Hydrolases
  2. Oxoreductases
  3. Oxidases
  4. Transferases
  5. Isomerases
  6. Lyases
  7. Ligases
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5
Q

What is the function of the hydrolase group of enzymes?

A
  • Catalyses the hydrolysis of a substrate by adding a molecule of water
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6
Q
A
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7
Q

What is an example of a hydrolase

A
  • DIgestive enzymes which work in our gut and can also be found in germinating seeds
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8
Q
A
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9
Q
A
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10
Q

What is an example of a hydrolase catlytic reaction

A
  • Maltone → maltase glucose + glucose
  • Lipid → Lipase fatty acids + glycerol
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11
Q

What is the function of oxyreductase

A
  • Oxoreductases are involved in oxidation and reduction reactions
    • i.e. Also known as redox reactions
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12
Q

What are two types of oxyreductases

A
  1. Dehydrogenases
  2. Oxidases
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13
Q

What is the function of dehydrogenases

A
  • Dehydrogenases oxidase the substrate by removing hydrogen, passing it on to a hydrogen acceptor or co factor
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14
Q

What is the function of oxidases

A
  • Catlyse the addition of oxygen to hydrogen forming water
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15
Q

What is the function of transferases

A

They transfer a group of atoms from one molecule to another

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16
Q
A
17
Q

What are two types of transferases

A
  1. Transaminases
    • Transfer amino acids (NH2) from one atom to another, enabling organisms to make certain types of amino acids
  2. Phosphotranferases
    • Control the transfer of phosphate groups in respiration
18
Q

What is the function of isomerases

A
  • Isomerases control the coversion of one isomer to another by transfering a group of atoms from one molecule to another
19
Q

What is the function of Lyases

A
  • Lyases break chemical bonds within the addition of water (hydrolysis)
20
Q

What is an example of a lyase

A
  • Decarboxylase is a Lyase which removes carboxyl groups from the respiratory substrates to release carbon dioxide
21
Q

What is the function of ligases

A
  • Ligases catluse reactions in which new chemical bonds are formed using ATP as a source of energy
    • e.g. DNA ligase is involved in the synthesis of DNA