Host-Defenses

Question 1

innate defense

Answer 1

properties of the normal host

NON-SPECIFIC defenses

Question 2

adaptive defences

Answer 2

induced by the infection

SPECIFIC to the pathogen aka based on ANTIGENS

Question 3

bacteriocin

Answer 3

normal microbiome secretes this

Question 4

complement system

Answer 4

• part of the innate defenses
• set of proteins that creates pores in the pathogen membrane and induces lysis
• activation: antibodies or microbial cell wall component
• no effect on gram positives

Question 5

inflammation

Answer 5

• general nonspecific response to endotoxins, tissue damage

- allows the recruitment of immune cells to the site of infection

Question 6

MAC

Answer 6

membrane attack complex

Question 7

granulocytes

Answer 7

phagocytic, granules in the cytoplam

Question 8

lymphocytes

Answer 8

B and T cells

Question 9

phagocytic cells

Answer 9

primarily neutrophils and mactophages

Question 10

ROS

Answer 10

rapid increase in uptake of O2 produces O2-, hydrogen peroxide, hydroxyl, OCl-
-need V-type ATPases, NADPH oxidase, Myeloperoxidase to get rid of them

Question 11

vasodilation

Answer 11

increased permeability

Question 12

diapedesis

Answer 12

passage of white blood cells through the intact walls of the capillaries

Question 13

C5a

Answer 13

attracts phagocytes

Question 14

C3a

Answer 14

causes a release of histamine by mast cells

Question 15

Il1

Answer 15

increase movement of fluid and immune cells to the infection sites

Question 16

Il1

Answer 16

increase movement of fluid and immune cells to the infection sites

• causes body temp to rise
• activates phagocytes and other immune cells

Question 17

Fever

Answer 17

:)

Question 18

Fever

Answer 18

produced by endotoxins