Host Defences Against Plaque Flashcards
What’re some characteristics of the innate immune system
- 1st line of defence
- rapid response
- non-specific
- no memory
what’re some characteristics of the adaptive/acquired immune system
- slow response
- specific
- memory cells
what’re 3 aspects of saliva that allow it to be a ‘defence barrier’
- washing effect (removes food & bac)
- protect mucosa
- antimicrobial (lysozymes/IgA)
what’re the functions of the inflammatory response
(5 [to, l, in, no, va])
- dilution of toxins
- movement of lymphatics
- prevent infections spreading
- destroys normal tissues too
- vasodilation
how is the classical pathway of the complement system activated
- binding IgM/IgG to antigen
- conformational change in Fc region of antibody
how is the alternate pathway of the complement system activated
+ what type of response is this usually relevant to
- spontaneous hydrolysis of C3 (without antibody)
- or activated by some PAMPs
- responsible for innate defence against bacterial biofilm
what’s gingival erythema
gingival inflammation
v. red
what’s gingival hyperplasia
gingival overgrowth
what’s oedema
swelling of the gingiva
what is the type of disease is gingivitis
rapid non-specific response to attack
what do histamines & bradykinins cause
vasodilation
increased vascular permeability
give an example of a red microbe
p.gingivalis
give some examples of orange microbes
prevotella
fusobacteria
