Hormones of the Kidney Flashcards

1
Q

__________ is produced by the peritubular capillary plexus endothelium.

A

Erythropoietin

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2
Q

Erythropoietin is produced when the O2 levels in the blood are (increased/decreased) ___________.

A

Decreased

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3
Q

When kidney fails, no erythropoietin is made so patient becomes severly _________.

A

anemic

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4
Q

The target tissues of ADH are two, ________ and ___________

A

Kidneys (DCT, CT)

Arterioles

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5
Q

The main function of _______ is to regulate body fluid osmolarity

A

ADH

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6
Q

Antineoplastic drugs are a (stimulatory/inhibitory) __________ factor of antidiuretic hormone secretion.

A

stimulatory

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7
Q

ANP release is a/an (stimulatory/inhibitory) _________ factor of ADH secretion.

A

inhibitory

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8
Q

The ___ receptor for antidiuretic hormone on vascular smooth muscles is coupled to phospholipase C by a Gq protein.

A

V1

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9
Q

Nicotine is a (stimulatory/inhibitory) ________ factor of

antidiuretic hormone secretion.

A

stimulatory

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10
Q

Increased pain is a (stimulatory/inhibitory) __________ factor of ADH secretion.

A

stimulatory

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11
Q

Decreased extracellular fluid volume is a (stimulatory/inhibitory) ____________ factor of antidiuretic hormone secretion.

A

Stimulatory

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12
Q

Opiates are a (stimulatory/inhibitory) _________ factor of antidiuretic hormone secretion.

A

stimulatory

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13
Q

Excess activity of parathyroid gland causes bone (resorption/mineralization) ____________.

A

Bone resorption

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14
Q

Hypofunction of parathyroid gland causes hypocalcemia, often with resultant _________.

A

tetany

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15
Q

__________ increases reabsorption of magnesium and hydrogen ions

A

PTH

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16
Q

_________ decreases the reabsorption of sodium, potassium and amino acids.

A

PTH

17
Q

______ receptor coupled to adenylyl cyclase by a Gs protein is the receptor for antidiuretic hormone on principal cells of the late distal tubule and collecting duct.

A

V2

18
Q

____________ channels in the luminal membranes allow for increased water permeability of principal cells in the late distal tubule and collecting duct, thus creating hyperosmotic urine.

A

Aquaporin 2

19
Q

Ethanol is an inhibitory factor for _________ secretion.

A

ADH