hormones

Question 1

gastrin

Answer 1

• increases gastric H+ secretion. stimulates growth of gastric mucosa
• stimulated by distention of stomach and vagal stimulation via GRP

Question 2

cholecystokinin (CCK)

Answer 2

• increase pancreatic enzyme and HCO3 secretion. stimulates contraction of gallbladder and relaxes sphincter. stimulates growth of exocrine pancreas. slows gastric emptying
• stimulated by fatty acids

Question 3

secretin

Answer 3

• increase pancreatic HCO3 secretion. increase biliary HCO3 secretion. decrease gastrin effects and H+ secretion
• stimulated by H+ and fatty acids in duodenum

Question 4

glucose-dependent insulinotropic peptide (GIP)

Answer 4

• increase insulin secretion from pancreatic B cells. decrease gastric H+ secretion.
• stimulated by oral glucose

Question 5

how to hormones travel

Answer 5

they are secreted into the portal circulation, pass through the liver, reach the systemetic circulation, and finally bind to target cell

Question 6

zollinger-ellison syndrome

Answer 6

• gastrin secreting tumor
  
  • increased gastrin levels
  • increased H+ levels
  • hypertophy of gastric mucosa
  • duodenal ulcers
  • steatorrhea