Hormonal interventions in addiction: the Gut Hormones in Addiction (GHADD) study

Question 1

NEED TO PANOPTO THIS

Systems involved in eating behaviour regulation?

Answer 1

Involvement of:
Hypothalamus, Midbrain (VTA), Nucleus solitary tract

External Cues
Food type

Internal Cues
hormones, ANS, gut, fat tissue
nutritional state
obesity
gender

Psychological Cues
eating behaviour
reward sensitivity
food preference

-> consumption

Question 2

Brain regions activated in response to palatable food or food assoc cues

Answer 2

DA innervation from midbrain and hypothalamus?

Amygdala: emotional response to cues

___

Dorsal striatum: habitual behaviour

Insula: taste cortex

OFC: salience evaluation

Question 3

How to examine food evaluation?

Answer 3

fMRI to examine response after showing pictures of energy varied foods and objects

Question 4

Food reward in obesity?

Answer 4

• increased inhibitory control
• increase salience response anticipatory reward
• decreased receipt response consummatory reward