Homeostasis And Intracellular Metabolism Flashcards
Homeostasis - definition and mechanism
• Condition where internal environment remains stable and inside a certain interval → reach equilibrium
• Nervous system and endocrine system working together or separately
Feedback systems
• Negative = fix equilibrium and most common
• Positive = accelerate change and often small part in bigger physiological process
• Feerforward mechanism = a warning which quickens start of process before changes occur
Metabolism - carbonhydrates
• Converted into glucose and absorbed during digestion
• Main source for ATP synthesis
• Glucose stored in muscles and liver
ATP SYNTHESIS
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Glycolysis (anaerobi) = glucose → glucose-6-phosphate → 2 pyruvic acids + 2 ATP + electrons and hydrogen stored in coenzymes
• In-between step = O2 + 2 pyrovic acids → 2 acetylCoA + CO2 (exhaled) + e- and H+ (into coenzyme) (if O2 not available it becomes lactate) - Kreb’s cycle (aerobic and in mitochondri) = 2 acetylCoA enters chemical chain circle and is broken down → 2 ATP + e- and H+ into coenzyme
- Oxidative phosphorylation (aerobic and in the inner membrane of mitochondria) = coenzymes enter cycle → e- into electron transport chain + O2 + H+ → 34 ATP + H2O
Metabolism- lipids
• Mostly broken down to triglycerides
• Can be stored or used to structure molecules: triglycerides → phospholipids + phosphate group
Lipolysis
• Lipids → monoglycerides → glucose → Glycolysis
• Lipids → fatty acids → acetylCoA → Kreb’s cycle