Homeostasis and Endocrine System Flashcards

1
Q

Definition of homeostasis

A

Maintenance of a constant internal environment

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2
Q

What is the internal environment regulated by

A

Autonomic nervous system
Endocrine system

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3
Q

What do positive feedback do

A

Amplify the change, deviation from the norm is not corrected

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4
Q

Give examples of positive feedback

A

Oxytocin for uterine contraction
Blood clotting

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5
Q

What is the endocrine system made up of

A

Hormones
Glands
Target cells
Communication

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6
Q

Give examples of endocrine glands

A

Testes
Ovary
thyroid gland
placenta
adrenal gland
hypothalamus
pituitary gland

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7
Q

What do adrenal glands release

A

cortisol and medulla adrenaline

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8
Q

Difference between endocrine and exocrine

A

Endocrine - no excretory ducts, hormones released locally/into blood, target cells

Exocrine - excretory duct, secretory products released through ducts

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9
Q

What produces thyroxine

A

thyroid gland

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10
Q

What stimulates thyroxine and form where

A

TSH - thyroid releasing hormone from pituitary gland

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11
Q

What regulates thyroxine and where from

A

TSH - thyrotropin releasing hormone from hypothalamus

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12
Q

Thyroxine target cells?

A

All cells

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13
Q

What are some major effects of thyroxine

A

Increase body temp + basal metabolic rate
Regulates growth hormone production
Calcium ion metabolism
Gonadal function
Lactation

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14
Q

Where is parathyroid hormone made

A

Parathyroid gland

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15
Q

What stimulates PTH

A

Low plasma calcium ion levels

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16
Q

Target for PTH

A

Bone, kidney (distal tubules)

17
Q

Major effects of PTH

A

Stimulates osteoclast breakdown to release Ca2+
Stimulate distal tubule of kidney to reabsorb Ca2+
Stimulates vitamin D production by kidney
Stimulate small intestine to increase absorption of Ca2+

18
Q

Where is calcitonin made

A

Thyroid gland

19
Q

What stimulates calcitonin

A

increase calcium ion levels

20
Q

Target for calcitonin

A

Bone, kidney

21
Q

Where is melatonin made

A

Pineal gland

22
Q

What stimulates melatonin

A

Lack of daylight - light suppresses melatonin production

23
Q

Target for melatonin

24
Q

Major effects of melatonin

A

reproduction - GnRH production

25
What cause release of aldosterone
Fall in blood pressure
26
What does aldosterone do
Increase Na+ absorption - lowers water potential - increase BP
27
What cause release of cortisol
Stress
28
How doe stress cause the release of cortisol
Induces hypothalamus to produce and release corticotropin releasing hormone CRH causes anterior pituitary to stimulate ACTH release which stimulates adrenal gland to release cortisol
29
Where is cortisol released from
adrenal gland
30
What does cortisol do
reduce CRH and ACTH - negative feedback
31
What can excess cortisol cause
Cushing's disease Weight gain hair loss lack of energy