Homeostasis Flashcards

1
Q

Components of Urine of a Healthy Person

A

Salts

Water

Uric Acids

Urea

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2
Q

Glucagon and Raising Blood Glucose

A

Alpha cells in the pancreas produce glucagon in response to low blood sugar to raise it

Glucagon prevents the conversion of glucose into fatty acids for storage, breaks down glycogen into glucose, and decreases respiration

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3
Q

Thermoregulation Mechanisms when Hot

A

Sweating: Sweat glands produce sweat that evaporates from the skin thus removing heat through evaporation

Vasodilation: Blood vessels in the skin dilate, which allows for more blood to flow to remove heat

Hairs Relax: Hairs lie flat against the skin, minimizing trapped air and promoting heat loss

Metabolic Rate Decreases: Thyroid gland produces less thyroxin which reduces body’s metabolic activity

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4
Q

Selective Reabsorption

A

The Proximal Convoluted Tubule is the longest part of the nephron, and over 80% of the filtrate is reabsorbed into the tissue fluid and then to the blood thus leaving the kidney

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5
Q

Process of Ultrafiltration

A

Since the afferent arteriole is much larger than the efferent, it builds up hydrostatic pressure inside the capillaries, forcing fluids to pass from the blood through the fenestrated capillaries in the glomerulus into the Bowman’s Capsule

The liquid then drains through the Bowman’s Capsule to the Proximal Convoluted Tubule

Large molecules like blood cells and proteins can’t pass through the Bowman’s Capsule, therefore have to return to the blood through the efferent arteriole

The liquid that passes through the Bowman’s Capsule is called Glomerular Filtrate, and includes water, salts and amino acids

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6
Q

Brain in Sleep, Vigorous Exercise, and Wakeful Rest

A

Sleep: High to support essential functions such as memory

Vigorous Exercise: High to meet the high metabolic demands and maintain cognitive function and coordination

Wakeful Rest: High to sustain cognitive function and consciousness while the body is awake and alert

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7
Q

Negative Feedback

A

When an organism does the opposite of a change to bring the organism’s conditions back to normal to maintain equilibrium

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8
Q

Loop of Henle

A

Has an ascending and descending limb

Ascending limb transports NaCl by diffusion and active transport out of the loop into the tissue fluid which increases solute concentration in tissue fluid and decreases solute concentration of the fluid in ascending limb itself

Descending limb has water move into the tissue fluid by osmosis, and NaCl diffuse from the tissue fluid into the loop

Fluid becomes more concentrated at the bottom of the loop, and animals that need to conserve water have very long loops of Henle to allow for more water to be reabsorbed

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9
Q

If Urine Contains ___?

A

Glucose, diabetes

Proteins, kidney disease or damage

Blood Cells, bacterial infection

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10
Q

Thermoregulation Process

A

Thermoreceptors in skin detect change in temperature and send signal to hypothalamus, the brain’s thermostat

Hypothalamus interprets the signals and determines whether temperature is rising or falling, and decides if the body cools down or heats up

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11
Q

Factors that Affect Volume and Concentration of Urine

A

Water intake

Temperature

Sugar or Salt Intake

Environmental Conditions

Degree / Amount of Exercise

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12
Q

Skeletal Muscles in Sleep, Vigorous Exercise, and Wakeful Rest

A

Sleep: Low due to inactivity

Vigorous Exercise: High to meet the increased demand for oxygen and nutrients required for muscle contraction

Wakeful Rest: Moderate, reflecting lower activity level compared to exercise

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13
Q

Structure of the Cells of the Tubules Adapted for Reabsorption

A

Microvilli: Increase the surface area of the inner surface

Pumps: Actively transport glucose and amino acids against their concentration gradient

Mitochondria: Provides ATP needed for Selective Reabsorption

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14
Q

Receptors, Control Centers, and Effectors

A

Receptors: Detect stimuli

Control Centers: Transfer information between different parts of the body

Effector: The muscle and glands that bring out a response

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15
Q

Osmoregulation

A

The process where the body regulates the solute concentration in its fluid by maintaining balance between water and electrolytes

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16
Q

Response to Thirst

A

Osmoreceptor cells in the hypothalamus detect the high osmolarity in the blood plasma and produce ADH, which gets released from the posterior pituitary

The ADH binds to receptors in the plasma membrane of cells in the collecting ducts which causes the cell to transport vesicles containing aquaporins towards the membrane and fuse with it, thus inserting aquaporins into the membrane

With more aquaporins embedded, more aquaporin channels open and increases the amount of water to passively diffuse by osmosis into the medulla, which produces small columns of concentrated urine

17
Q

Differences in Blood Concentrations between Renal Artery and Vein

A

Wastes: High in artery and low in vein as it’s excreted in urine

Oxygen: High in artery and low in vein as it’s used in cell respiration by kidney tissue

Glucose: High in artery and low in vein as it’s used in cell respiration by kidney tissue

Drugs / Toxins: High in artery and low in vein as it’s excreted in urine

Carbon Dioxide: Low in artery and high in vein as it’s produced by cell respiration and excretion of kidney cells

Ions: Vary in both as it depends on amount of water reabsorbed in the collecting duct in response to ADH

18
Q

Type 1 VS Type 2 Diabetes

A

Insulin is not being produced
Pancreas doesn’t respond to insulin

Genetic and environmental factors
Age and diet and genetics

During childhood
During adulthood

No proven cure
Lifestyle modifications such as diet and exercise

Requires insulin injections to regulate blood sugar
Medication and managing lifestyle

19
Q

Kidney in Sleep, Vigorous Exercise, and Wakeful Rest

A

Sleep: Moderate to maintain renal function

Vigorous Exercise: Moderate and decreased slightly as blood is redirected to active tissues

Wakeful Rest: Moderate to ensure filtration and regulation of blood composition

20
Q

Afferent and Efferent Arterioles

A

Blood arrives to the nephron in the afferent arterioles and delivers to network of capillaries called a glomerulus in a cup shaped structure called Bowman’s Capsule

Blood leaves the glomerulus in the efferent arteriole which is narrower than the afferent arteriole

21
Q

Response to Hydrated

A

ADH levels decrease, thus the walls of the collecting ducts allow less water to pass into the blood thus less water is conserved by the body, which produces dilute urine

22
Q

Conditions for Ultrafiltration

A

Hydrostatic Pressure due to the difference in diameter between afferent and efferent arteriole

Basement Membrane to restrict the passage of large molecules such as blood cells and proteins

23
Q

What Separates Glomerulus and Lumen

A

Endothelium: 1 cell thick with more gaps than other capillaries

Basement Membrane: Made of network of collagen and glycoprotein

Podocytes: Cells with tiny finger like projections that make up the lining of the Bowman’s capsule that wrap around the blood vessels of the glomerulus

24
Q

Gut in Sleep, Vigorous Exercise, and Wakeful Rest

A

Sleep: Low as body’s metabolic activity decreases

Vigorous Exercise: Low as blood is redirected to other vital organs involved in exercise

Wakeful Rest: Moderate to support ongoing digestive processes and nutrient absorption from food intake

25
Q

Kidney Structure

A

Blood enters through the renal artery and drained through the renal vein

Surrounded by a tough capsule, outer region is cortex and inner is medulla

Central region is the pelvis which leads to the ureter

26
Q

Excretory Organs

A

Kidneys: Excrete excess water

Liver: Converts excess amino acids into urea

Lungs: Gets rid of carbon dioxide and water vapor

Sweat Glands: Excretes water, salts, and toxins

27
Q

Importance of Osmoregulation in Animals

A

If water uptake is excessive, hydrostatic pressure can stretch the plasma membrane to the point of bursting

If water loss is excessive, the cell will shrink and die as water is an essential for the cell’s cytoplasm

28
Q

Insulin and Lowering Blood Glucose

A

Beta cells in the pancreas produce insulin in response to high blood sugar to lower it

Insulin converts glucose into fatty acids for storage, stores glucose as glycogen, and increases respiration

29
Q

Collecting Duct

A

After loop of Henle, the fluid moves to the collecting duct where the high solute concentration establishes an osmotic gradient. Water in the filtrate can passively diffuse out into the blood thus making the urine more concentrated

The water leaves through aquaporins which are controlled by ADH, which allows for the amount of water in urine to be controlled

30
Q

Homeostasis

A

Keeping internal conditions stable within limits

31
Q

Thermoregulation Mechanisms when Cold

A

Shivering: Muscles contract to generate heat

Vasoconstriction: Blood vessels in the skin constrict which reduces blood flow to minimize heat loss

Hairs Contract: Hairs stand, trapping a layer of insulating air next to the skin (Goosebumps)

Metabolic Rate Increases: Thyroid gland produces more thyroxin which increases body’s metabolic activity