Homeostasis Flashcards
Explain how insulin reduces the blood glucose concentration (3)
- More insulin binds to receptors
- Stimulates uptake of glucose by channel proteins
- Activates enzymes which convert glucose to glycogen
Explain the action of glucagon (3)
- Attaches to receptors on target cells and activates enzymes
- Glycogen to glucose
- Gluconeogenesis
Explain the effect of sweating or panting on temperature control (2)
- Evaporation of water
- Heat transferred from blood
Describe how a change in blood pH or blood pressure can cause a change in heart rate (6)
- CO2 detected by chemoreceptors and pressure detected by baroreceptors
- Medulla involved
- More impulses to SA
- Decrease pH detected by chemoreceptors in carotid artery
- Sends impulses to medulla
- More nerve impulses sent by sympathetic nervous system to SAN
Less CO2 in the blood leads to a reduction in heart rate. Describe how (5)
- Detected by chemoreceptors
- Located in carotid artery
- Fewer impulses to medulla oblongata
- More impulses along parasympathetic nerve
- To SAN
Describe the secondary messenger model (3)
- Adenylate cyclase is activated and converts ATP to cAMP
- Activates protein kinase enzymes
- Glycogenolysis ang gluconeogenesis occurs
Describe the role of glycogen formation and its role in lowering the blood glucose levels (4)
- Glucose concentration in liver falls
- Below that in the blood plasma
- Creates concentration gradient
- Glucose enters cell by facilitated diffusion
Describe how blood glucose levels can be increased using hormones (3)
- Release of glucagon
- Leads to formation of glucose in liver cells
- From non-carbohydrates and fatty acids
Describe how ultrafiltration occurs in a glomerulus (4)
- Higher than normal high hydrostatic pressure
- Small molecules such as water, urea and ions leave
- Pass through fenestrations in endothelium of capillary
- Through basement membrane
Explain why a thicker medulla leads to more concentrated urine (3)
- Thicker medulla so longer loop of henle
- Increase Na+ concentration so Na+ gradient maintained for longer
- Water potential gradient maintained so more water reabsorbed by osmosis
Describe the action of ADH in the kidney (4)
- Permeability of membrane is increased
- More water absorbed from distal convoluted tubule
- Smaller volume of urine
- Urine becomes more concentrated
Explain why glucose is found in the urine of a person with untreated diabetes (3)
- High concentration of glucose in blood
- Not all glucose is reabsorbed at proximal convoluted tubule
- Carrier proteins are working at maximum rate
What is meant by negative feedback? (1)
An increase or decrease from the set point, the opposite is instigated so returns the value back to the norm
What is meant by the term positive feedback? (1)
Deviation from the optimum causes even greater deviation from the normal
What is meant by the term positive feedback? (1)
Deviation from the optimum causes even greater deviation from the normal