Homeopathy reflections Flashcards
what are the 3 things in the evidence based medicine paradigm
best evidence
patient values
clinical expertise
what actually happens in dilution
may increase particle size
not sure at higher dilutions
whats a nanoparticle
particles between 1 and 100nm
a particle is defined as a small object that behaves as a whole unite with respect to its transport properties
homesis evidence?
stimulatory effects caused by small amounts of toxic substance
hydroid, bacteria, yeast
the hierarchy of evidence
meta analysis of RCTs (combing data from multiple studies) individual RCT observational studies basic research clinical experience
what are non systemic narrative reviews
review with no attempt to look at literature
what did non conventional statistics conclude
high quality studies more likely to be negative
more high quality studies needed
what control trial is used
30 year old trial
subjective outcomes
35% drop out
already included in meta analysis
why do they use fibromyalgia for studies
not effectively treated
not well defined
subjective symptoms
mercurius vivus
slow
chills alternate with heat
offensive breath
slimy bloody stools
arsenicum album side effects
anxiety and restlessness
cold sweats
vomiting
burning stools
issues with homeopathy evidence
limited evidence, at best mixed
meta analysis is abunch of poor trials put together
more rigorous trials yield smaller effects
publication bias cochrane reviews do not show that homeopathic medicines have effects beyond placebo
canadian regulations
have DIN-HM
limits to products
12C or greater required for certain products
health canada regulated
homeopathic use considered acceptable evidence
what level of evidence is needed for homeopathic medicine
peer reviewed published articles, conclusions from other reputable regulatory agencies, previous marketing experience….
regulation in US
FDA approval safe and effective
focuses on safety
philosophy of freedom and choice