Hodgkin Lymphoma Flashcards
Hodgkin lymphoma things you must know
Younger patients, good prognosis
Contiguous spread
Five subtypes
Reed-Sternberg cell
morphology HL
reed-sternberg cell (owl cells)
HL subtypes
Nodular lymphocyte-predominance Hodgkin lymphoma
Classical Hodgkin lymphoma: Nodular sclerosis Lymphocyte rich Mixed cellularity Lymphocyte depletion
Nodular L-P HL things you must know
Asymptomatic young male with cervical lymphadenopathy
Good prognosis (early stage)
B-cell origin
Popcorn cells
morphology NLPHL
Popcorn cells
classical presentation NLPHL
Asymptomatic young male with cervical lymphadenopathy
Nodular sclerosis HL things you must know
Most common subtype Good prognosis (early stage) Lacunar cells
morphology NSHL
Lacunar Cells
Mixed Cellularity HL things you must know
Worse prognosis
Usually disseminated at presentation
Classic Reed-Sternberg cells
Mixture of background cells (eosinophils, histiocytes)
Lymphocyte rich HL things you must know
Uncommon
Usually localized at presentation
Popcorn cells
morphology lymphocyte-rich HL
popcorn cells
Lymphocyte depletion HL things you must know
Rare
Often disseminated at presenation
Class R-S cells
collagen or reticulin background
morphology lymphocyte depletion HL
Classic Reed-sternberg cells
collagen or reticulin background
treatment/prognosis of HL
Surgery, chemo, radiation
Prognosis depends on stage
Danger: second malignancies
morphology mixed cellularity HL
Classic R-S Cells
Mixture of background cells (eosinophils, histiocytes, etc)
