ALL

Question 1

ALL stands for

Answer 1

acute lymphoblastic leukemia

Question 2

ALL things you must know

Answer 2

Malignant proliferation of lymphoid blasts in blood, bone marrow
Classified by immunophenotype (B vs. T)
More common in children
Prognosis often good!

Question 3

All ALL are what positive?

Answer 3

TdT+

marker in lymphoblasts

Question 4

ALL classified by

Answer 4

immunophenotype

Question 5

t cell vs b cell ALL

Answer 5

T cell worse prognosis than B cell

Question 6

T lymphoblastic leukemia same as

Answer 6

T lymphoblastic lymphoma

Question 7

T-cell ALL classic presentation

Answer 7

Teenage male with mediastinal mass

Question 8

B cell lymphoblastic leukemia same as

Answer 8

B-cell lymphoblastic lymphoma

Question 9

what does B cell leukemia sometimes have cytogenetics

Answer 9

philadelphia chromosome (worse prognosis)

Question 10

prognosis ALL - age

Answer 10

Good if 1-10, not good in babies, gets worse as get older

Question 11

cytogenetics of ALL

Answer 11

hyperdiploidy is good

Question 12

tx ALL

Answer 12

chemo +/- bone marrow transplant

many children are cured