Hodgkin Lymphoma Flashcards
What is the staging system used to describe the features of Hodgkin lymphoma
The Ann Arbor Staging System
What letters can be included with the four stages of Hodgkin lymphoma?
A- The patient does not have B symptoms
B- The patient has B symptoms
E- Extranodal disease is present
S- Disease is found in the spleen
In advanced stages, what is the pattern of spread for Hodgkin lymphoma?
To the viscera, spleen, liver, bone marrow or other organs
What is the primary treatment modality for early stage Hodgkin Lymphoma?
Chemotherapy
For stage 1 & 2 Hodgkin lymphoma, what is the standard treatment regimen?
ABVD (Adriamycin, Bleomycin, Vincristine, Dacarbazine) chemotherapy
What is salvage therapy?
When chemotherapy is used after the disease has reoccurred in an area already treated with radiation therapy
True/false The progression of Hodgkin’s lymphoma is typically less predictable than that of non-Hodgkin’s lymphoma
false
Which Hodgkin’s lymphoma symptoms are under B category (multiple answers)
a) Fever
b) Coughing
c) Dysphagia
d) Frequent night sweats
e) Weight gain
f) Unexplained weight loss
a, d, f
What is the combined field name for the following fields
- Neck
- Chest
- Axilla
Mantle field
What is the combined field name for the following fields
- Pelvis
- Para-aortic fields
Inverted Y
What is the combined field name for:
mantle field
spleen
LNs in the upper abdomen and pelvic area
Total Nodal Radiation
What is the combined field name for:
mantle field
spleen
LNs in the upper abdomen
Subtotal Nodal Radiation
What is the combined field name for a treatment area that only encompass the areas of known disease?
Involved Field Radiation
What is the combined field name for a treatment area that includes areas of known disease and contiguous uninvolved LNs?
Extended Field Radiation
Why is treatment to pelvic region avoided?
To preserve fertility for patients with a favorable prognosis.
What should be done if there is a treatment failure for a Hodgkin lymphoma patient?
- Autologous bone marrow transplant
- Peripheral blood stem cell transplant.
Before conducting a autologous bone marrow transplant or peripheral blood stem cell transplant, what must be done?
High doses of radiation/chemo to the whole body to destroy cancer cells & bone marrow tissue to suppress the immune system.
Immune system suppression helps prevent the body from rejecting the new stem cells.
An individual requires a pelvic radiation treatment plan being built. What combined field is typically utilized with this type of case & what comprises the field?
Inverted Y ~ abdominal (para-aortic LNs) & Pelvic field
(T or F) Radiation is more effective alone than utilized in conjunction with chemotherapy.
False; Radiation is more effective in conjunction with chemotherapy.
For an individual that is receiving pelvic irradiation for HL (Hodgkin lymphoma), what is the dose range if radiation is given in conjunction with chemotherapy?
Up to 20 Gy
For an individual that is receiving pelvic irradiation to an area free of disease, what is the dose range?
35 to 44 Gy
For an individual that is receiving pelvic irradiation to an area of initial nodal involvement, what is the dose range?
25 to 30 Gy
(T or F) When treating a large field size, it is crucial to spare as much healthy tissue
TRUE
What are the two kinds of NHL?
Indolent and aggressive
