HLA Compatibility Testing Flashcards
1
Q
Hematopoietic Stem Cell Transplant (HCT)
A
entire immune system is transferred; recipient is totally immunodeficient for a period of time
2
Q
autologous transplant
A
patients own stem/progenitor cells harvested & returned
can be used if malignancy is not genetic
patient must have sufficient CD34+ cells
3
Q
allogeneic transplant
A
patients own immune system is destroyed & replaced with stem cells of another person
matches from siblings are ideal
4
Q
origin of anti-HLA antibodies
A
transfusions
pregnancies
previous transplants
5
Q
anti-HLA antibodies are what class?
A
all are IgG not IgM