HLA Compatibility Testing Flashcards

1
Q

Hematopoietic Stem Cell Transplant (HCT)

A

entire immune system is transferred; recipient is totally immunodeficient for a period of time

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2
Q

autologous transplant

A

patients own stem/progenitor cells harvested & returned
can be used if malignancy is not genetic
patient must have sufficient CD34+ cells

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3
Q

allogeneic transplant

A

patients own immune system is destroyed & replaced with stem cells of another person
matches from siblings are ideal

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4
Q

origin of anti-HLA antibodies

A

transfusions
pregnancies
previous transplants

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5
Q

anti-HLA antibodies are what class?

A

all are IgG not IgM

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