HIV-Astle Flashcards

1
Q

What are the backbone of ARV regimens?

A

Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTI)

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2
Q

NRTI

A

Zidovudine
Didanosine
Stavudine
Lamivudine
Abacavir
Tenofovir disoproxil
Emtricitabine
Tenofovir alafenamide

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3
Q

NRTI co-formulations

A
  • Abacavir/lamivudine (Epzicom)
  • Tenofovir disoproxil fumarate/emtricitabine (Truvada)
  • Tenofovir alafenamide/emtricitabine (Descovy)
  • Lamivudine/tenofovir disoproxil fumarate (Cimduo)
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4
Q

Abacavir/lamivudine

A

Epzicom

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5
Q

Tenofovir disproval fumarate/emtricitabine

A

Truvada

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6
Q

Tenofovir alafenamide/emtricitabine

A

Descovy

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7
Q

Lamivudine/tenofovir disoproxil fumarate

A

Cimduo

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8
Q

Zidovudine

A

Retrovir

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9
Q

Didanosine

A

Videx

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10
Q

Stavudine

A

Zerit

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11
Q

Lamivudine

A

Epivir

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12
Q

Abacavir

A

Ziagen

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13
Q

Tenofovir disoproxil fumarate

A

Viread

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14
Q

Emtricitabine

A

Emtriva

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15
Q

Tenofovir alafenamide

A

Vemlidy

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16
Q

Which NRTIs are renally eliminated?

A

lamivudine (Epivir)
TDF (Viread)
Emtricitabine (Emtriva)

17
Q

Which NRTIs are eliminated hepatically?

A

abacavir (Ziagen)

18
Q

Which NRTI has a SE of renal insufficiency (increased SCr), decreased BMB, Fanconi syndrome, HA, N/V/D

A

Viread

19
Q

Protease Inhibitor (PI)

A
  • Ritonavir (Norvir)
  • Darunavir (Prezista)
20
Q

PI co-formulations

A
  • Ataznavir/cobicistat (Evotaz)
  • Darunavir/cobicistat (Prezcobix)
    -Darunavir/cobicistat/emtricitabine/tenofovir alafenamide (Symtuza)
21
Q

Ritonavir

A

Norvir

22
Q

Darunavir

A

Prezista

23
Q

atanavir/cobicistat

A

Evotaz

24
Q

darunavir/cobicistat

A

Prezcobix

25
Q

darunavir/cobicistat/emtricitabine/tenafovir alafenamide

A

Symtuza

26
Q

NNRTIs

A
  • Efavirenz (Sustiva)
  • Etravirine (Intelence)
  • Rilpivirine (Durant)
  • Doravirine (Pilfetro)
27
Q

NNRTIs co-formulations

A

Atripla
Complera
Odefsey
Delstrigo
Symfi, Symfi Lo

28
Q

Sustiva

A

Efarivenz

29
Q

Intelence

A

Etravirine

30
Q

Edurant

A

Rilpivirine

31
Q

Doravirine

A

Pilfetro

32
Q

Efavirenz/emtricitabine/tenofovir disoproxil fumarate

A

Atripla

33
Q

Rilpivirine/emtricitabine/tenofovir disoproxil fumarate

A

Complera

34
Q

Rilpivirine/emtricitabine/tenofovir alafenamide

A

Odefsey

35
Q

Doravirine/tenofovir disoproxil fumarate/lamivudine

A

Delstrigo

36
Q

Efavirenz/lamivudine/tenofovir disoproxil fumarate

A

Symfi, Symfi Lo

37
Q
A