HIV-Astle

Question 1

What are the backbone of ARV regimens?

Answer 1

Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTI)

Question 2

NRTI

Answer 2

Zidovudine
Didanosine
Stavudine
Lamivudine
Abacavir
Tenofovir disoproxil
Emtricitabine
Tenofovir alafenamide

Question 3

NRTI co-formulations

Answer 3

• Abacavir/lamivudine (Epzicom)
• Tenofovir disoproxil fumarate/emtricitabine (Truvada)
• Tenofovir alafenamide/emtricitabine (Descovy)
• Lamivudine/tenofovir disoproxil fumarate (Cimduo)

Question 4

Abacavir/lamivudine

Answer 4

Epzicom

Question 5

Tenofovir disproval fumarate/emtricitabine

Answer 5

Truvada

Question 6

Tenofovir alafenamide/emtricitabine

Answer 6

Descovy

Question 7

Lamivudine/tenofovir disoproxil fumarate

Answer 7

Cimduo

Question 8

Zidovudine

Answer 8

Retrovir

Question 9

Didanosine

Answer 9

Videx

Question 10

Stavudine

Answer 10

Zerit

Question 11

Lamivudine

Answer 11

Epivir

Question 12

Abacavir

Answer 12

Ziagen

Question 13

Tenofovir disoproxil fumarate

Answer 13

Viread

Question 14

Emtricitabine

Answer 14

Emtriva

Question 15

Tenofovir alafenamide

Answer 15

Vemlidy

Question 16

Which NRTIs are renally eliminated?

Answer 16

lamivudine (Epivir)
TDF (Viread)
Emtricitabine (Emtriva)

Question 17

Which NRTIs are eliminated hepatically?

Answer 17

abacavir (Ziagen)

Question 18

Which NRTI has a SE of renal insufficiency (increased SCr), decreased BMB, Fanconi syndrome, HA, N/V/D

Answer 18

Viread

Question 19

Protease Inhibitor (PI)

Answer 19

• Ritonavir (Norvir)
• Darunavir (Prezista)

Question 20

PI co-formulations

Answer 20

• Ataznavir/cobicistat (Evotaz)
• Darunavir/cobicistat (Prezcobix)
  -Darunavir/cobicistat/emtricitabine/tenofovir alafenamide (Symtuza)

Question 21

Ritonavir

Answer 21

Norvir

Question 22

Darunavir

Answer 22

Prezista

Question 23

atanavir/cobicistat

Answer 23

Evotaz

Question 24

darunavir/cobicistat

Answer 24

Prezcobix

Question 25

darunavir/cobicistat/emtricitabine/tenafovir alafenamide

Answer 25

Symtuza

Question 26

NNRTIs

Answer 26

- Efavirenz (Sustiva) - Etravirine (Intelence) - Rilpivirine (Durant) - Doravirine (Pilfetro)

Question 27

NNRTIs co-formulations

Answer 27

Atripla Complera Odefsey Delstrigo Symfi, Symfi Lo

Question 28

Sustiva

Answer 28

Efarivenz

Question 29

Intelence

Answer 29

Etravirine

Question 30

Edurant

Answer 30

Rilpivirine

Question 31

Doravirine

Answer 31

Pilfetro

Question 32

Efavirenz/emtricitabine/tenofovir disoproxil fumarate

Answer 32

Atripla

Question 33

Rilpivirine/emtricitabine/tenofovir disoproxil fumarate

Answer 33

Complera

Question 34

Rilpivirine/emtricitabine/tenofovir alafenamide

Answer 34

Odefsey

Question 35

Doravirine/tenofovir disoproxil fumarate/lamivudine

Answer 35

Delstrigo

Question 36

Efavirenz/lamivudine/tenofovir disoproxil fumarate

Answer 36

Symfi, Symfi Lo