catheter infections - bug/drug

Question 1

MSSA preferred

Answer 1

PCN, oxacillin, nafcillin

Question 2

MSSA alternative

Answer 2

ampicillin/sulbactam; cefzolin (PCN-IgE-mediated allergy)

Question 3

MRSA preferred

Answer 3

vancomycin

Question 4

MRSA alternative

Answer 4

daptomycin, linezolid, tedizolid, dalbavancin, oritavancin, ceftaroline

Question 5

MS-CoNS preferred

Answer 5

oxacillin, nafcillin

Question 6

MS-CoNS alternative

Answer 6

ampicillin/sulbactam, cefazolin, (PCN-IgE-mediated allergy)

Question 7

MR-CoNS preferred

Answer 7

vancomycin

Question 8

MR-CoNS alternative

Answer 8

daptomycin, linezolid, dalbavancin, oritavancin

Question 9

Enterococcus spp (E. faecalis, E. faecium) preferred

Answer 9

ampicillin

Question 10

Enterococcus spp (E. faecalis, E. faecium) alternative

Answer 10

ampicillin-R: vancomycin
vancomycin-R: daptomycin, linezolid, tedizolid, oritavacin

Question 11

Enterobacterales preferred

Answer 11

ESBL (-): ceftriaxone
ESBL (+): carbapenem

Question 12

Enterobacterales alternative

Answer 12

ESBL (-): cefepime, FQ (C&L)
ESBL (+): FQ (C&L)
MDRO: ceftazidime/avibactam, cefepime/enmetazobactam, cefiderocol, l/c/relabactam, meropenem/vaborbactam

Question 13

P. aeruginosa preferred

Answer 13

cefepime, ceftazidime

Question 14

P. aeruginosa alternative

Answer 14

piperacillin/tazobactam, carbapenem (M,D, l/c), FQ (C&L)
MDRO: ceftazidime/avibactam, ceftolozane/tazobactam, cefidderocol, l/c/relabactam

Question 15

Acinetobacter spp. preferred

Answer 15

ampicillin/sulbactam

Question 16

Acinetobacter spp alternative

Answer 16

cefepime, meropenem, l/c, ceftazidime/avibactam, cefiderocol