HIV Antiretroviral Agents Flashcards
Nucleoside Reverse Transcriptase Inhibitors
NRTIs
Brand: Tenofovir Alafenamide
Generic: None
Code: TAF
Food:
TOD:
Dose Adj: Renal
Major ADR: Lactic Acidosis, Hepatic Steatosis, HBV flare (w/ DC)
Nucleoside Reverse Transcriptase Inhibitors
NRTIs
Brand: Viread
Generic: Tenofovir Disoproxil Fumarate
Code: TDF
Food:
TOD:
Dose Adj: Renal
Major ADR: Lactic Acidosis, Hepatic Steatosis, HBV flare (w/ DC), Nephrotoxicity, Osteopenia
Nucleoside Reverse Transcriptase Inhibitors
NRTIs
Brand: Emtriva
Generic: Emtricitabine
Code: FTC
Food:
TOD:
Dose Adj: Renal
Major ADR: Lactic Acidosis, Hepatic Steatosis, HBV flare (w/ DC)
Nucleoside Reverse Transcriptase Inhibitors
NRTIs
Brand: Epivir
Generic: Lamivudine
Code: 3TC
Food:
TOD:
Dose Adj: Renal
Major ADR: Lactic Acidosis, Hepatic Steatosis, HBV flare (w/ DC)
Nucleoside Reverse Transcriptase Inhibitors
NRTIs
Brand: Ziagen
Generic: Abacavir
Code: ABC
Food:
TOD:
Dose Adj: Hepatic
Major ADR: Lactic Acidosis, Hepatic Steatosis, HLA-B*5701 hypersensitivity, CV risk
Nucleoside Reverse Transcriptase Inhibitors
NRTIs
Brand: Zidovudine
Generic: None
Code: AZT
Food:
TOD:
Dose Adj: Renal
Major ADR: Lactic Acidosis, Hepatic Steatosis, Cytopenias
Non-Nucleoside Reverse Transcriptase Inhibitors
NNRTIs
Brand: Sustiva
Generic: Efavirenz
Code: EFV
Food: w/o bc dec ADR
TOD: Night bc dc AM ADR
Dose Adj: Hepatic
Major ADR: Rash, Hepatotxicity, CNS Effects
Non-Nucleoside Reverse Transcriptase Inhibitors
NNRTIs
Brand: Edurant
Generic: Rilpivirine
Code: RPV
Food: w/ bc inc Abs
TOD:
Dose Adj: Renal, Hepatic
Major ADR: Rash, Hepatotxicity, Renal Virologic Response (Low VL/CD4), Depression, QTc prolongation
Non-Nucleoside Reverse Transcriptase Inhibitors
NNRTIs
Brand: Intelence
Generic: Entravirine
Code: ETR
Food: w/ bc inc Abs
TOD:
Dose Adj: Hepatic
Major ADR: Rash, Hepatotxicity, Inc Lipids, Inc Glucose
Non-Nucleoside Reverse Transcriptase Inhibitors
NNRTIs
Brand: Viramune
Generic: Nevirapine
Code: NVP
Food:
TOD:
Dose Adj: Hepatic
Major ADR: Rash, Hepatotxicity, Rash/Hepatotoxicity Contraindications (based on Gender and CD4 Count)
Protease Inhibitors
PIs
Brand: Prezista
Generic: Darunavir
Code: DRV
Food: w/ dec GI upset
TOD:
Dose Adj: Hepatic
Major ADR: Hyperglycemia, Hyperlipidemia, Hepatotoxicity, Nausea/GI Upset, Rash
Protease Inhibitors
PIs
Brand: Reyataz
Generic: Atazanavir
Code: ATV
Food: w/ inc Abs
TOD:
Dose Adj: Renal, Hepatic
Major ADR: Hyperglycemia, Hyperlipidemia, Hepatotoxicity, Hyperbilirubinemia
Protease Inhibitors
PIs
Brand: Kaletra
Generic: Lopinavir/Ritonavir
Code: LPV/r or LPV/RTV
Food:
TOD:
Dose Adj: Hepatic
Major ADR: Hyperglycemia, Hyperlipidemia, Hepatotoxicity, Diarrhea
Protease Inhibitors
PIs
Brand: Lexiva
Generic: Fosamprenavir
Code: FPV
Food:
TOD:
Dose Adj: Hepatic
Major ADR: Hyperglycemia, Hyperlipidemia, Hepatotoxicity, Diarrhea
Integrase Inhibitors
INSTIs
Brand: Tivicay
Generic: Dolutegravir
Code: DTG
Food:
TOD:
Dose Adj: Renal, Hepatic
Major ADR: Inc SCr (non-toxic)