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Infectious Disease > Antibiotics Beta Lactams > Flashcards

Antibiotics Beta Lactams Flashcards

1
Q

Beta Lactams
Penicillins
Natural

A

Penicillin G

PK/PD = T>MIC

Form: IV, IM-Benz, IM-Proc

Renal: Yes

ADR/DDI: Seizure, Na/K Elevation

Tx: Strep

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2
Q

Beta Lactams
Penicillins
Natural

A

Penicillin V

PK/PD: T>MIC

Forms: PO

Renal: Yes

ADR/DDI: Seizure, Na/K Elevation

Tx: Strep

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3
Q

Beta Lactams
Penicillins
Amino

A

Ampicillin

PK/PD: T>MIC

Forms: IV, PO

Renal: Yes

ADR/DDI:

Tx: Strep

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4
Q

Beta Lactams
Penicillins
Amino

A

Amoxicillin

PK/PD: T>MIC

Forms: PO

Renal: Yes

ADR/DDI:

Tx: Strep

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5
Q

Beta Lactams
Penicillins
Amino BL/BLI (β-lactam /β-lactamase inhibitor)

A

Ampicillin + Sulbactam

PK/PD: T>MIC

Forms: IV

Renal: Yes

ADR/DDI:

Tx: Broad Spectrum Enteric Anaerobes

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6
Q

Beta Lactams
Penicillins
Amino BL/BLI (β-lactam /β-lactamase inhibitor)

A

Amoxicillin + Clavulanate

PK/PD: T>MIC

Forms: PO

Renal: Yes

ADR/DDI: Diarrhea

Tx: Broad Spectrum Enteric Anaerobes

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7
Q

Beta Lactams
Penicillins
Extended Spectrum

A

Piperacillin + Tazobactam

PK/PD: T>MIC

Forms: IV

Renal: Yes

ADR/DDI:

Tx: Broad Spectrum Enteric Anaerobes, PsA

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8
Q

Beta Lactams
Penicillins
Anti-Staph

A

Nafcillin

PK/PD: T>MIC

Forms: IV

Renal: No

ADR/DDI: Hepatitis, Neutropenia, Acute Interstitial Nephritis (AIN)

Tx: MSSA

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9
Q

Beta Lactams
Penicillins
Anti-Staph

A

Oxacillin

PK/PD: T>MIC

Forms: IV

Renal: No

ADR/DDI: Hepatitis, Neutropenia, Acute Interstitial Nephritis (AIN)

Tx: MSSA

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10
Q

Beta Lactams
Penicillins
Anti-Staph

A

Dicloxacillin

PK/PD: T>MIC

Forms: PO

Renal: No

ADR/DDI:

Tx: MSSA

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11
Q

Bata Lactams
Cephalosporins
1st Generation

A

Cephalexin

PK/PD: T>MIC

Forms: PO

Renal: Yes

ADR/DDI:

Tx: GP: Strep, MSSA, GN: PEK (Proteus mirabilis, E. coli, and Klebsiella pneumoniae)

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12
Q

Bata Lactams
Cephalosporins
1st Generation

A

Cefazolin

PK/PD: T>MIC

Forms: IV

Renal: Yes

ADR/DDI:

Tx: GP: Strep, MSSA, GN: PEK (Proteus mirabilis, E. coli, and Klebsiella pneumoniae)

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13
Q

Bata Lactams
Cephalosporins
2nd Generation

A

Cefuroxime

PK/PD: T>MIC

Forms: IV, PO

Renal: Yes

ADR/DDI:

Tx: GP: Strep, MSSA, GN: HNPEK (Hemophilus influenzae, Neisseria meningitidis, Proteus mirabilis, E. coli, and Klebsiella pneumoniae)

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14
Q

Beta Lactams

Cephamycins

A

Cefoxitin

PK/PD: T>MIC

Forms: IV

Renal: Yes

ADR/DDI:

Tx: GP: Strep, MSSA, GN: HNPEK (Hemophilus influenzae, Neisseria meningitidis, Proteus mirabilis, E. coli, and Klebsiella pneumoniae), and Anaerobes

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15
Q

Beta Lactams

Cephamycins

A

Cefotetan

PK/PD: T>MIC

Forms: IV

Renal: Yes

ADR/DDI:

Tx: GP: Strep, MSSA, GN: HNPEK (Hemophilus influenzae, Neisseria meningitidis, Proteus mirabilis, E. coli, and Klebsiella pneumoniae), and Anaerobes

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16
Q

Bata Lactams
Cephalosporins
3nd Generation

A

Ceftriaxone

PK/PD: T>MIC

Forms: IV

Renal: No

ADR/DDI: Neonatal jaundice, Biliary sludging

Tx: GP: Strep, MSSA, GN: HENPEK (Hemophilus influenzae, Enterobacteriaciae, Neisseria meningitidis, Proteus mirabilis, E. coli, and Klebsiella pneumoniae)

17
Q

Bata Lactams
Cephalosporins
3nd Generation

A

Cefotaxime

PK/PD: T>MIC

Forms: IV

Renal: Yes

ADR/DDI:

Tx: GP: Strep, MSSA, GN: HENPEK (Hemophilus influenzae, Enterobacteriaciae, Neisseria meningitidis, Proteus mirabilis, E. coli, and Klebsiella pneumoniae)

18
Q

Bata Lactams
Cephalosporins
3nd Generation

A

Cefpodoxime

PK/PD: T>MIC

Forms: PO

Renal: Yes

ADR/DDI:

Tx: GP: Strep, MSSA, GN: HENPEK (Hemophilus influenzae, Enterobacteriaciae, Neisseria meningitidis, Proteus mirabilis, E. coli, and Klebsiella pneumoniae)

19
Q

Bata Lactams
Cephalosporins
3nd Generation

A

Cefixime

PK/PD: T>MIC

Forms: PO

Renal: Yes

ADR/DDI:

Tx: GP: Strep, MSSA, GN: HENPEK (Hemophilus influenzae, Enterobacteriaciae, Neisseria meningitidis, Proteus mirabilis, E. coli, and Klebsiella pneumoniae)

20
Q

Bata Lactams
Cephalosporins
3nd Generation

A

Ceftazidime

PK/PD: T>MIC

Forms: IV

Renal: Yes

ADR/DDI:

Tx: GP: Strep, GN: HENPEK (Hemophilus influenzae, Enterobacteriaciae, Neisseria meningitidis, Proteus mirabilis, E. coli, and Klebsiella pneumoniae), PsA

21
Q

Bata Lactams
Cephalosporins
4th Generation

A

Cefepime

PK/PD: T>MIC

Forms: IV

Renal: Yes

ADR/DDI: Encephalopathy

Tx: GP: Strep, MSSA, GN: HENPEK (Hemophilus influenzae, Enterobacteriaciae, Neisseria meningitidis, Proteus mirabilis, E. coli, and Klebsiella pneumoniae), PsA

22
Q

Bata Lactams
Cephalosporins
5th Generation

A

Ceftaroline

PK/PD: T>MIC

Forms: IV

Renal: Yes

ADR/DDI:

Tx: MRSA

23
Q

Beta Lactams
Cephalosporins
BL/BLI (β-lactam /β-lactamase inhibitor)

A

Ceftazidime + Avibactam

PK/PD: T>MIC

Forms: IV

Renal: Yes

ADR/DDI:

Tx: PsA, ESBL (Extended spectrum β-lactamase), CRE (Carbapenam Resistant)

24
Q

Beta Lactams
Cephalosporins
BL/BLI (β-lactam /β-lactamase inhibitor)

A

Ceftaroline + Tazobactam

PK/PD: T>MIC

Forms: IV

Renal: Yes

ADR/DDI:

Tx: PsA, ESBL (Extended spectrum β-lactamase)

25
Q

Beta Lactams

Monobactam

A

Aztreonam

PK/PD: T>MIC

Forms: IV

Renal: Yes

ADR/DDI:

Tx: PsA, NO GP

26
Q

Beta Lactams
Carbapenems
Anti-PsA

A

Imipenem

PK/PD: T>MIC

Forms: IV

Renal: Yes

ADR/DDI: Seizure (lmi)

Tx: PsA, ESBL (Extended spectrum β-lactamase), Anaerobes

27
Q

Beta Lactams
Carbapenems
Anti-PsA

A

Meropenem

PK/PD: T>MIC

Forms: IV

Renal: Yes

ADR/DDI: Seizure (lmi)

Tx: PsA, ESBL (Extended spectrum β-lactamase), Anaerobes

28
Q

Beta Lactams
Carbapenems
Anti-PsA

A

Doripenem

PK/PD: T>MIC

Forms: IV

Renal: Yes

ADR/DDI: Seizure (lmi)

Tx: PsA, ESBL (Extended spectrum β-lactamase), Anaerobes

29
Q

Beta Lactams
Carbapenems
Non-Anti-PsA

A

Ertapenem

PK/PD: T>MIC

Forms: IV

Renal: Yes

ADR/DDI:

Tx: PsA, ESBL (Extended spectrum β-lactamase), Anaerobes, Acinetobacter

Infectious Disease (3 decks)

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