HIV/AIDS Flashcards
signs/sx of acute HIV
2-6 wks post exposure
“flu like”
pt highly infectious
Rash (upper trunk, neck, face)
acute HIV labs
HIV Ab test - negative
Viral load >10,000
Increased LFTs
leukopenia
thrombocytopenia
how long from getting HIV does a pt seroconvert?
within 3 mos of infection
HIV stays active in what part of body
lymph nodes
how long can HIV stay latent
10 yrs
clinical latency period labs
CD4 T cell count decreases
sx of clinical latency
asx or lynphadenopathy
sx infection signs
fatigue.malaise
mouth disorders: oral hairy leukoplakia (viral EBV)
Kaposis sarcoma
sx infection labs
RNA viral load increases
CD4 T cell count decreases
progression to AIDS definition
CD4 T cell count <200
or
HIV + 1 out of 27 AIDS defining conditions regardless of CD4 T cell count
Pneumocytis Jiroveci CPx
severe hypoxemia
fever, cough SOB
CXR of PJP
diffuse/perihilar infiltrates
PJP dx
sputum sample
labs PJP
increased LDH
PJP tx
bactrium DS
CD4 T cell count PJP
<200
CPx toxoplasmosis
encephalitis
intracranial lesions
HA
focal neuro deficits
seizures
retinitis, pneumonitis
toxo dx
mult. contrast enhancing lesions on brain on MRI or CT
seropositive for toxo
toxo tx
sulfadiazine & pyrimethamine
CD4 T cell count for toxo
< 100
MAC CPx
systemic dz in adv HIV
night sweats
wt loss
abd pain
Diarrhea
anemia
MAC dx
sputum AFB stain positive
positive sputum & Blood cultures
MAC tx
macrolide
CD4 T cell count for MAC
<50
