HIV/AIDs Flashcards

1
Q

What are targets of HIV therapy

A

Entry Inhibitors
Integrase Inhibitors
Reverse Transcriptase Inhibitors
Protease inhibitors

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2
Q

HIV process with CD4

A

Bind to CD4 receptors on T helper
convert its RNA to DNA and insert into T helper
Lie dormant
Leave cell and kill T helper cell upon leaving

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3
Q

What are normal levels of T helper CD4 cells

A

500 - 1500

AIDS < 300

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4
Q

What is viral load

A
# of copies of HIV in small amount of blood
- as viral load increases closer to AIDS
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5
Q

What are treatments

A

HAART - Highly active antiviral retrospective therapy

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6
Q

What are laboratory markers of HIV infection

A

Viral load - HIV replication rate

CD4 count - immunologic damage

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7
Q

What are opportunistic infections with AIDS

A
Bacterial
- TB
- Strep pneumonia
Viral
- Kaposi Sarcoma
- Herpes
- Influenza
Parasitic
- Pneumocystis carinii
Fungal
- Candida
- Cryptococcus
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8
Q

What are the 5 ā€œPā€s for HIV

A
Sexual Practices
Past STD
Pregnancy History
Protection from STD
Partners in last 6 months/1 year
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9
Q

What is HIV mgmt after diagnosis

A
q 3 month followup
primary care and specialty care
pharmacy
nutrition
mental health
cervical and anal pap smears
cholesterol screening
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10
Q

What is PrEP in HIV

A

pre-exposure prohylaxis for HIV

Take before and during periods of risk

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