HIV Flashcards

1
Q

two receptors that HIV virus gain entry into cell?

A

CXCR4 and CCR5

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2
Q

what is the enzyme HIV has to change into DNA?

A

reverse transcriptase

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3
Q

main treatment for HIV?

A

anti retro virals

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4
Q

What is the method of treatment we use and what does that mean?

A
2 + 1 therapy
2 nucleoside reverse transcriptase inhibitors plus 1 of something else
protease inhibitor
entry inhibitors
fusion inhibitors
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5
Q

prophylaxis for HIV?

A

emtricitabine and tenofavir

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6
Q

what to give mom if she has HIV and baby is coming out?

A

AZT

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7
Q

3 risk factors for HIV to remember

A

sex
drug use
vertical transmission for baby

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8
Q

cd4 count of what is aids?

A

200

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9
Q

two ways pts will usually present with HIV?

A
antiretroviral syndrome (acute HIV infection)
opportunistic infection
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10
Q

What will the patient preset like with acute HIV infection?

A

flu but they will be flu, mono and elisa negative

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11
Q

How to make diagnosis of acute HIV infection?

treat?

A

PCR, viral load

2+1

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12
Q

how to make the diagnosis when they are presenting with opportunistic infection?
confirmatory test?

A

ELISA, or antibodies

western blot

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13
Q

3 other pieces of information when managing HIV patients and why?

A

viral load
CD4 count
genotype to see which meds will be best

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14
Q

What infection are you worried about with CD4 count dropping below 200? what can we use for prophylaxis?

A

PCP

bactram, or dapsone if cant tolerate

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15
Q

CD4 less than 100

prophylaxs?

A

toxo

bactram

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16
Q

CD4 less than 50

prophlaxis?

A

mac

azithromycin

17
Q

what to give to treat PCP and why would you use steroids?

A

bactrim

steroids if oxygen is low

18
Q

what do you give for PCP prophylaxis if G6PD defiency?

A

atovaquone

19
Q

Purple papules in Aids is what?

A

kaposi sarcoma HHV8