HIV Flashcards
Respiratory AIDS defining illnesses
- TB
- Pneumocystis pneumonia
Neuro AIDS defining illnesses
- Toxoplasmosis
- Primary cerebral lymphoma
- Cryptococcal meningitis
- Progressive multifocal leukoencephalopathy
Derm AIDS defining illnesses
Karposi’s sarcoma
Cancer AIDS defining illnesses
- Karposi’s sarcoma
- Non-Hodgkins lymphoma
- Cervical cancer
Opthamology AIDS defining illnesses
CMV retinitis
ENT conditions that might suggest (but not define) AIDS
- lymphadenopathy (unknown cause)
- chronic parotitis
- lymphoepithelial parotid cysts
Gynae conditions that might suggest (but not define) AIDS
- vaginal intraepithelial neoplasia
- cervical intraepithelial neoplasia (Grade 2 or higher)
GI conditions that might suggest (but not define) AIDS
- oral thrush
- oral hairy leukoplakia
- Hep B or C
- salmonella, shigella, campylobacter
- Chronic diarrhoea/ unintended weight loss
Respi conditions that might suggest (but not define) AIDS
- bacterial pneumonia
- aspergillosus
Derm conditions that might suggest (but not define) AIDS
- seborrhoice dermatitis (recurrent)
- psoriasis (recurrent)
- HZV infection (recurrent)
Which virus causes Karposi’s sarcoma
Herpes human virus 8
Symptoms of seroconversion (primary HIV infection)
- Fever
- Lymphadenopathy
- Rash
- Pharyngitis
3 types of drugs given in HAART
2 NRTIs + 1 other agent
NRTI = NucleoSide analogue reverse transcriptase inhibitor
3 Types of reverse-transcriptase inhibitors
- Non-nucleoside reverse transcriptase inhibitors (NNRTI)
- Nucleoside analogue reverse transcriptase inhibitors (NRTIs)
- Nucleotide analogue reverse transcriptase inhibitors (NtRTIs)
3 main viral enzymes that HIV drugs can work on
- Reverse transcriptase inhibitors
- Protease inhibitors
- Integrase inhibitors