Hepatitis

Question 1

Which liver enzymes are raised in hepatitis

Answer 1

raised ALT
raised AST
raised GGT

Question 2

General symptoms of hepatittis

Answer 2

• fever, arthralgia
• hepatomegaly
• abdominal pain

Question 3

Which antibiotic may cause jaundice, and give an obstructive picture on LFTs

Answer 3

co-amoxiclav

Question 4

Which Hep virus(es) only present acutely

Answer 4

Hep A

Question 5

Which Hep virus(es) may present acutely or chronic

Answer 5

Hep B, C, D, E

Question 6

Which virus is the commonest cause of acute hepatitis in UK

Answer 6

Hep E

Question 7

Which group of people is most likely to develop chronic hepatitis after an acute infection

Answer 7

Children

Question 8

Which hepatitis viruses have vaccines

Answer 8

Hep A
Hep B
Hep C

Question 9

definition of chronic hepatitis

Answer 9

> 6 months

Question 10

Treatment for Hep A

Answer 10

Supportive (fluids, manage temperature and jaundice, stop hepatotoxic drugs)

Question 11

Treatment for Hep B, C, D, E

Answer 11

• interferons

- antivirals

Question 12

What does this show:

• -ve: HBs-Ag
• +ve: anti-HBc, anti-HBs

Answer 12

Hep B immunity after infection

Question 13

What does this show:

• -ve: HBs-Ag , anti-HBc
• +ve: anti-HBs

Answer 13

Hep B immunity after vaccination

Question 14

What does this show:

• -ve: anti-HBs, anti-HBc (IgM)
• +ve: HBs-Ag , HBe-Ag, HBc-Ag, anti-HBc (IgG)

Answer 14

Chronic Hep B infection

Question 15

What does this show:

• -ve: anti-HBs
• +ve: HBs-Ag , HBe-Ag, HBc-Ag, anti-HBc (IgM)

Answer 15

Acute Hep B infection

Question 16

IgM and IgG - which is acute/ chronic?

Answer 16

IgM = acute
IgG = chronic

Question 17

Among the hepatitis viruses with potential to become chronic, which has highest risk of becoming chronic

Answer 17

Hep C

Question 18

In which countries is Hep E highly endemic

Answer 18

Nigeria, India, China, Mexico