HIV Flashcards
1
Q
Maraviroc
A
Binds host CCR5, prevents CCR5-topic-HIV-1 entry
Resistance due to mutations in gp120
2
Q
Enfuvirtide
A
Binds to gp41 and inhibits viral fusion and entry
Resistance due to mutations in gp41
3
Q
NRTIs
A
Nucleos(t)ide reverse transcriptase inhibitors
Chain termination
4
Q
NNRTIs
A
Non-nucleos(t)ide reverse transcriptase inhibitors
Allosteric modulators of RT
Examples: Delaviridine, Efavirenz, Etravirine, Neviraine, Rilpivirine
5
Q
Protease Inhibitors
A
Target HIV protease
End in -avir
6
Q
Intregrase Strand Transfer Inhibitors
A
Prevent provirus integration
End in -gravir
