HIV Flashcards
HIV
retrovirus that destroy CD4 cells
risk factors
unprotected anal, vaginal or oral sex
vertical transmission
common in the gay community
infected blood or bodily fluids
what are the typical stages for HIV
seroconversion - symptomatic
asymptomatic stage
AIDS - immunocompromised
seroconversion signs
sore throat lymphadenopathy malaise oral ulcers unwell
investigations
combination test of HIV antibody and p24antigen
when can tests be repeated
to confirm an initial positive test in 12 weeks
double check a negative test 12 weeks after
how do you monitor disease
CD4 count
management and when do you start
antiretroviral therapy
give at the time of diagnosis
at what CD4 count do symptoms start to appear
<200
complications
pneumocystis jiroveci pneumonia diarrhoea kapsoi's sarcoma - purple papules on skin, mucosa lymphoma oesophageal candidas neuro complications
what should be done if the CD4 count is <200
prophylaxis of pneumocystis jiroveci pneumonia
co-trimoxazole
when should a follow up test be done in asymptomatic patients
4 weeks
what neuro complications can occur
EBV
John Cunningham
what is a common cause of diarrhoea in HIV
cryptospondum
can you give live vaccines
nada