History and Structure of DNA Flashcards

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1
Q

what did griffith use in his experiment?

A

mice

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2
Q

what disease was griffith studying

A

pneumonia

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3
Q

when injected with the virulent s-strain

A

the mice died

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4
Q

when injected with the r-strain

A

the mice lived

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5
Q

when injected with heat killed s-strain

A

the mice lived

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6
Q

when injected with heat killed s-strain and r strain

A

the mice died

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7
Q

griffith concluded that genetic material had been taken from the s-strain. He called this

A

transformation

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8
Q

Avery’s experiment involved the same things as griffiths except,

A

avery treated the solution with different enzymes to remove different biomolecules

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9
Q

when the mice were injected with the DNA-ase treated solution,

A

the transformation did not occur

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10
Q

what is the molecule of heredity?

A

DNA

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11
Q

what were the two biomolecules that scientists thought could be the molecule of heredity?

A

DNA and protein

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12
Q

why did scientists not believe that DNA was the molecule of heredity?

A

they thought it was too simple to do such an important task

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13
Q

nucleotides are made up of phosphate group,

A

a sugar, and a nitrogenous base

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14
Q

pyrimidines have

A

1 ring

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15
Q

which bases are pyrimidines?

A

thymine, cytosine

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16
Q

purines have

A

2 rings

17
Q

which bases are purines?

A

adenine and guanine

18
Q

true or false: pyrimidines always pair with purines

A

true

19
Q

thymine pairs with

A

adenine

20
Q

cytosine pairs with

A

guanine

21
Q

Is DNA double or single stranded?

A

double stranded, forms a double helix structure

22
Q

Is RNA double or single stranded?

A

single stranded, folds over itself

23
Q

True or False: In RNA, adenine is replaced with uracil.

A

False. In RNA, uracil replaces thymine

24
Q

Which carbons form covalent bonds that create the sugar phosphate backbone of DNA and RNA molecules?

A

3’ and 5’