histopathology of periodontal disease Flashcards

1
Q

Why is enamel not shown in histology

A

high mineralisation

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2
Q

Junctional epithelium and use in diagnosis

A

attached to the enamel and ACJ

- important in gingival health identification

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3
Q

normal sulcus depth helathy

A

0.5 to 2mm

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4
Q

what does the acquired pellicle allow

A

plaque can colonise on the tooth surface

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5
Q

most normal gingiva are.. due to

A

middle inflamed due to thin layer of plaque on teeth

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6
Q

PDL fibre function

A

attach into cementum and alveolar bone

helps maintain integrity of periodontium

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7
Q

in health what attaches to what

A

junctional epithelium attaches at the aDJ

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8
Q

stages in gingivitis and peridontonal disease

A

early gingivitis
chronic marginal gingivitis
destructive periodontitis

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9
Q

early gingivitis

A

initial changes occur in 1st week as plaque accumulates

early lesion occur in the 2nd week

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10
Q

chronic marginal gingivitis

A

established lesion
occurs within 2-3 weeks if there is no change to OH
can either remain stable for a long period or develop rapidly

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11
Q

destructive periodontis

A

the advanced lesion

timescale is unknown

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12
Q

where is plaque found and acts as..

A

accumulates at gingival margin

acts as an irritant and noxious stimulant

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13
Q

what does plaque accumulation lead to

A

vasodilation (increased blood flow)
oedema development
formation of crevicular fluid, flows out through gingival margin
neutrophulcs migrate to fight stimulus

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14
Q

what is the aim of formation of crevicular fluid

A

attempts to flush the noxious stimuli out

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15
Q

What happens at the junctional epithelium

A

susceptible to bacterial infection
very wide intracellular spaces
cells can be rapidly turned over

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16
Q

clinical signs of early gingivitis

A

gingiva is redder (erythematous) - due to increased vasculature dilation
gingiva still attached to tooth and ACJ

17
Q

what is the cellular reponce t early gingivitis

A

epithelium proliferates (to protect)
rete pegs
fibroblasts show signs of damage
recruitment of macrophages and lympocytes

18
Q

clinical signs of chronic gingivitis

A

loss of stippled gingiva due to inflamed tisue
gums erythematic
rounding of interdental papilla
BOProbing
small parts of plaque found on tooth surface

19
Q

cellular reponce to chronic gingivitus

A

increase in vascularity (no. blood vessels) and formation of crevicular fluid
increase in lymphocytes and plasma cells
junctional epithelium becomes detached from teeth (still remains at ACJ)

20
Q

why does the junctional epithelium detach from teeth during chronic gingivitus

A

expansion of the tissue due to oedema and looseness of the tissue

21
Q

what can happen to and at the junctional epithelium

A

may become ulcerated
- loss of collagen but fibres inserting into cementum still intact
sulcus may appear depended but no true pocket formation
plaque and bacteria can fill the small pocket (psudopocket as it it still attached at ACJ)
projections rather than flat(rete pegs)

22
Q

rete ridges in chronic gingivitus

A

elongated rete ridges into underlying connective tissue

23
Q

what does chronic gingititus lead to

A

destructive periodontitis

24
Q

cellular response to destructive periodontitis

A

loss of collagen fibres insetting into cementum
junctional apitheliummigrates to cementum below ACJ - true pocket formation
destruction of alveolar bone, loss of PDL fibres

25
Q

what does the true pocket formation allow

A

biofilm can develop apically

damage tissue on its way down via bacterial biproducts

26
Q

clinical signs of destructive periodontis

A

recessing of gingival margin from aCJ apically
probe of true pockets
mobility of teeth due to loss of attachments and loss of alveolar bone

27
Q

what is seen on a radiograph of destructive perioontits

A

significant bone loss

28
Q

management of destructive peridontisis

A

root surface debridement
OH measures
- aim to remove plaque, calculus and debris

29
Q

what happens when. a patient complies with management of periodontis

A

inflammation subsides
attaches to tooth (long epithelial attachment)
little or no regeneration of bone or collagen fibres inserting in cementum

30
Q

summary of gingivitus

A
response to plaque accumulation
acute then chronic inflammation response
no bone destruction
junctional epithelium at ACJ
reversivle
31
Q

summary of destructive periodontal diseas

A
unknown what causes progression
loss of collagen fibres into cememntum
true pocket
JE apical onto cementum
destrcuction of alveolar bone
irreversible
32
Q

when JE attaches directly onto cementum after destructive peritonitis it is called

A

long epithelial attachment