Histology of Oral Cavity Flashcards

1
Q

The oral mucosa is composed of ___________ epithelium overlying a connective tissue layer called the ____________.

A

Stratified squamous; lamina propria

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2
Q

What is the function of the oral mucosa?

A

Provides protection, sensation, and secretion

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3
Q

What are three basic types of oral mucosa?

A
  • Masticatory
    • Covers areas experiencing masticatory forces
    • Palate
    • Gingiva
  • Lining
    • Buccal, labial and alveolar mucosa
    • Covers floor, cheecks, lips, soft palate
  • Specialized
    • Dorsal tongue surface
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4
Q

Which basic type of oral mucosa is being descibed below?

  • Resilent and rubbery
  • Not stretcy’Forms a firm base in attached gingiva and hard palate
  • Does not gape after incisions
  • ​Painful with injection or inflammation
A

Masticatory

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5
Q

Masticatory mucosa is also known as ________.

A

Mucoperiosteum

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6
Q

Which type of oral mucosa is being described below?

  • Orthokeratinized
  • Overlies lamina, propria, with little or no submucosa
A

Masticatory Mucosa

NOTE: Masticatory mucosa is also often parakeratized

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7
Q

What are the characteristics of parakeratinized epithelium?

A
  • Surface cells retain pyknotic nuclei
  • The granular layer has few granules of keratohyaline (filaggrin)
  • Little submucos
  • Prickle layer has high density of desmosomes.

NOTE: Parakeratinized is normal for oral mucosa but abnormal for skin

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8
Q

Which type of oral mucosa is being described below?

  • Non-keratinized
  • Flexible and stretchy
  • Moist
  • Gapes after incision
  • Injection easy, but so is spread of infection
A

Lining mucosa

NOTE: Lining mucosa is thicker than masticatory mucosa in most areas

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9
Q

Which surfaces are covered by lining mucosa?

A
  • Inside of lips
  • Cheeks
  • Floow of mouth
  • Underside of tongue
  • Soft palate
  • Alveolar mucosa
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10
Q

Which basic type of oral mucosa is being described below?

  • Nonkeratinized stratified squamous epithelium
  • Has three layers, with gradual transitions
  • With migration to surface, cells enlarge, but retain nuclei and do not die
  • Submucosa usaully present, overlying muscle
A

Lining mucosa

NOTE: Lining mucosa is very thin under tongue, which is important for drug delivery

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11
Q

What are the layers of lining mucosa?

A
  • Superifical layer
  • Intermediate layer
  • basal layer
  • Lamina propria
  • Submucosa
  • Muscle
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12
Q

The ________ contrasts the keratinized masticatory mucosa of attached gingiva with nonkeratinized lining of mucosa of alveolar mucosa.

A

Mucogingival Junction

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13
Q

Label

A
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14
Q

Characteristics of attached gingiva

A
  • Keratinized (or parakeratinized) epithelium
  • Many large collagen bundles in lamina propria to attach to periosteum (stippling)
  • High rete pegs (epithelial extensions projecting into the underlying connective tissue)
  • No submucosa (mucoperiosteum)
  • Pale pink or darkly pigmented.
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15
Q

Characteristics of alveolar mucosa

A
  • Thicker nonkeratinized epithelium
  • Loose lamina propria with elastic fibers
  • Thick submucosa
  • Bright pink; vasculature is rich and lies near the epithelium
  • Minor salivary glands in submucosa
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16
Q

Type of lingual papillae

A
  • Filiform
  • Circumvallate
  • Fungiform
  • Foliate
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17
Q

Which type of papillae is being described below?

  • No taste buds
  • Very sensitive to touch
  • Cones of thick keratinized epithelium, only located on anterior 2/3rd
  • Nonkeratinized areas in between
  • Reduced with age
A

Filiform papillae

NOTE: A= Thick keritinazed epithelium; B= Nonkeratinized areas

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18
Q

Which type of papillae is being described below?

  • Few
  • Larhe
  • Each surrounded by deep trench containing taste buds
    • Surface is covered by keratinized epithelium, but trench walls are nonkeratinized
A

Circumvallate papillae

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19
Q

Label

A
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20
Q

Which type of papillae is being described below?

  • Scattered between filiform papillae on tip of tongue
  • Red because of highley vascular core and thin epithelium
  • Taste buds are most present on superior surface
  • Sensitive to touch, as well as taste
A

Fungiform Papillae

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21
Q

Which type of papillae is being described below?

  • Leaflike folds on lateral margin of posterior tongue
  • Few taste buds in lateral walls
  • Nonkeratized epithelium
  • ​Lost with age
A

Foliate Papillae

*Note lymphoid tissue in opposing fold

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22
Q

Label

A

Lingual Tonsil

NOTE: Lingual tonsil is a collection of lymphoid follicles, which crypts opening onto the surface of the tongue. Covered by nonkeratized epithelium

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23
Q

The lingual tonsiled is lined by ________ epithelium.

A

Non-keratinized lining epithelium

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24
Q

Turnover time

A

Time necessary to replace all cells

*Very rapid in oral mucosa

NOTE: The quick turnover rate allows rapid, scar-free healing, but tendency to oral ulcers under chemotherapy

25
Q

Approximate cell turnover in oral mucosa

A
26
Q

Label

A

A = enamel,

B = dentin

D = pulp,

E = alveolar bone

F = periodontal ligament

27
Q

What are the 4 main components of teeth?

A
  • Enamel
  • Dentin
  • Dental pulp
  • Peridontal ligament
28
Q

Which major component of teeth is being described below?

  • Hardest biological tissue, but brittle
  • 96% minaral crystals
  • Little matrix
  • Avascular; non-vital
  • No nerves
  • Non-renewable
  • Ionic exchange with saliva
A

Enamel

29
Q

Which major component of teeth is being described below?

  • Harder than bone
  • Resilient, slightly elastic
  • 70% mineral, 20% protein matrix, 10% water
  • Smaller crystals
  • Blood vessels and nerves
  • Grows through life
  • Can repair itself
A

Dentin

A= dentin

B= enamel

30
Q

Dental pulp is made up of __________ tissue.

A

Loose connective tissue

31
Q

Function of dental pulp

A

Forms, maintains, and repairs dentin

NOTE: Dental pulp is especially rich in blood and nerve supply and continues to function and form dentin throughout life

32
Q

The periodontal ligament is made of _______ tissue.

A

Dense fibrous connective tissue

33
Q

Function of periodontal ligament

A

Secures teeth to jaw

34
Q

Gomphosis

A

Peg and socket joint that contains proprioceptors for protective reflexes

35
Q

Functions of saliva

A
  • Lubrication during mastication, swallowing, and speech
  • Buffering
  • Ions for maturation and maintenance of tooth enamel
  • Growth factrs for wound healing and maintenance of mucosa
  • Antibacterial, antiviral
  • Initiation of digestion
  • Taste: Solubilize food, flush and maintain taste buds
36
Q

3 Major Salivary Glands

A

Parotid

Submandibular

Sublingual

37
Q

Xerostomia

A

“Dry mouth”

  • May be caused by radiotherapy, loss of innervation, autoimmune diseases or anti-cholinergic drug effects
  • Leads to rampant caries, mucosal infections, fungal infections, atrophy of oral mucosa, and difficulties in tasting, swallowing and speaking
38
Q

Normal flow of saliva

A

500-750 ml/day

39
Q

Which salivary glands are mediated by nerves?

A

parotid and submandibular

NOTE: Minor glands and sublingual secrete continuously

40
Q

_______ (parasymphatetics/sympathetics) stimulate fluid flow. ___________(parasympathetics/sympathetics) decrease fluid.

A

Parasympathetics; sympathetics

41
Q

____________ (parasympathetics/sympathetics) activete protein exocytosis.

A

Sympathetics

42
Q

Label

A
43
Q

Characteristics of serous secretion

A
  • Round nuclei in base
  • Basal basophilic rER
  • Extensive Golgi
  • Apical secretions granules
44
Q

Mechanism of serous secretion

A
  1. Active transport of ions into cell draws water in
  2. Apical anion channels open with parasympathetic activation, drawing ions and water into the lumen, creating and isotonic primary saliva
  3. As saliva moves through ducts, salt is pumped out, leaving a hypotonic saliva
45
Q

___________ cells encircle acini and intecalated ducts.

A

Myoepithelial cells

NOTE: Myoepithelial cells lie between the epithelial secretory cells and the basal lamina

46
Q

Function of myoepithelial cells

A

Creates secretory pressure

47
Q

Label

A

SA= Serous acini

InD= Intercalated ducts

48
Q

____________ express isotonic fluid into intercalated ducts, then into striated ducts with simple columnar epithelium.

A

Serous acini

49
Q

Which ions are added in the striated duct?

A

Bircarbonate

Kallikrein

K+

50
Q

How are LM striations created?

A
51
Q

Characteristics of mucous secretion

A
  • Nuclei flat and compressed agaist basal edge
  • Apical cytoplasm filled with poorly stained mucous secretory granules
  • Lumen is larger and more tubular
  • Golgi and rER present, but constricted
52
Q

Mucin granules are discharged under ______ control.

A

Nervous

53
Q

Serous demilunes are an artifact of _________.

A

Fixation

NOTE: All secretory cells contact the lumen

54
Q

Characterize each salivary gland as serous, mucous or mixed.

A

Parotid gland

  • All serous acini; fat cells

Submandibular

  • Mixed; mostly serous

Sublingual

  • Mixed; mostly mucous
55
Q

Characteristics of minor salivary glands

A
  • No capsule (not so painful with swelling)
  • Rich in mucins, antibacterial proteins and IgA
  • Slow, continuous secretion
56
Q

Function of (Von) Ebner’s Glands

A
  • Release secretions into the trench surroungding the vallate papilla, flushing to enhance taste discrimination
57
Q

Sjogren’s syndrome

A

Autoimmune disorder involving salivary and lacrimal glands

58
Q

What type of gland are salivary glands?

A

Merocrine

59
Q

Classification of Glands

A