Histology of gastrointestinal system Flashcards
Layers of the mucosa
Epithelium- mucus secreting
Layers of the mucosa
Lamina Propria-MALTS for immune survailence ( lymphocytes, plasma cells)
Layers of the mucosa
Muscularis mucosae-Causes movement of mucosa. Innervated by parasympathetic
Submucosa
Very vascular
Tunica muscularis
Smooth muscle. Inner=circular m. outer=longitudinal m. Between layers is a parasympathetic myenteric plexus
Tunica externa
known as tunica adventitia
mucosa structure
stratified squamous in oral cavity, pharynx, esophagus, anal canal. Stomach has secretory glands. small intestine has villi and large intestine has mucus glands
Muscularis mucosae
extend into lamina propria and villi
Tunica muscularis function
peristalsis which is inherent but regulated by ANS, hormones, environmental influences.
Esophagus
upper 1/3 & lower 1/3 have seromucous glands. Upper 1/3 of tunica muscularis contains skeletal muscle, middle 1/3 is mixed, lower 1/3 is smooth muscle.
Esophageal sphincter
Physiologic and involved contraction of diaphragm, Aboral peristalsis, Intra abdominal pressure
Stomach
Mechanical and chemical functions
muscle layers in the stomach
innermost is oblique, inner (middle) circular, outer is longitudinal
Gastric glands
1-7 glands that empty into lumen at a single gastric pit. Glands are straight tubular with base, neck , isthmus opening into it
Parietal cells
Large, round , eosinophilic cytoplasm. tubulovesicular system, Short microvilli, Carbonic acid is produced in cells which dissociates into hydrogen and bicarbonate ions. Vesicles of tubulovesicular system may bud off into canaliculi so that HCL is produced in lumen of canaliculi
Chief cells
basophilic cytoplasm, secrete pepsinogen
pepsinogen
stored in zymogen granules and cleaves to become pepsin in low ph
Stem cells
replace all kinds of gastric cells by migrating up and down gland
Neuroendocrine cells
secrete hormones, serotonin