Histology of connective tissues

Question 1

What colour do collagen fibres stain?

Answer 1

pink

Question 2

What type of connective tissue has…
Widely spaced collagen fibres
Fibroblasts/fibrocytes
unstained ground substance

Answer 2

Loose connective tissue

Question 3

What cells can connective tissue cells be derived from?

Answer 3

mesenchymal cells

haematopoeitic stem cells

Question 4

Osteoblasts are derived from which cell?

Answer 4

mesenchymal cells

Question 5

Chondrocytes are derived from which cell?

Answer 5

mesenchymal cells

Question 6

Collagen, elastin and reticulin are all examples of what type of fibre?

Answer 6

Visible fibres

Question 7

What part of connective tissue does not stain with H&E?

Answer 7

ground substance

Question 8

What comprises ground substance?

Answer 8

proteoglycans
glycosaminoglycans
invisible fibres

Question 9

laminin and fibronectin are examples of what type of fibre?

Answer 9

invisible fibres

Question 10

What are the 4 types of connective tissue?

Answer 10

loose fibrous
dense fibrous
hard
fatty

Question 11

What type of connective tissue is cartilage?

Answer 11

hard connective tissue

Question 12

What do fibroblasts secrete that forms collagen?

Answer 12

tropocollagen subunits

Question 13

Where is collagen assembled?

Answer 13

extracellularly

Question 14

Describe tropocollagen

Answer 14

triple helix of peptides

Question 15

What type of collagen is in the skin?

Answer 15

type 1

Question 16

What type of collagen is in the cartilage?

Answer 16

type 2

Question 17

Type 1 collagen is found in which part of the body?

Answer 17

the skin

Question 18

Type 2 collagen is found in which part of the body?

Answer 18

catilage

Question 19

What type of collagen is reticulin and where is it found?

Answer 19

reticulin is type 3 collagen

reticulin is found in the liver, spleeen and bone marrow

Question 20

what type of collagen is present in basement membranes?

Answer 20

type IV

Question 21

In which part of the body would you find type V collagen?

Answer 21

placenta

Question 22

Describe what the difference between loose and dense connective tissue is?

Answer 22

In loose connective tissue- widely spaced thin collagen fibres
In dense connective tissue- closely spaced thick collagen fibres

Question 23

What subtypes of dense connective tissue are there?

Answer 23

irregular dense connective tissue

regular dense connective tissue

Question 24

What is the difference between regular and irregular dense connective tissues?

Answer 24

regular- regularly arranged collagen fibres

irregular- haphazardly arranged collagen fibres

Question 25

Why does reticulin require a silver stain?

Answer 25

It is not visible on H&E

Question 26

What does reticulin form in many organs?

Answer 26

A supporting scaffold

Question 27

What colour do elastin fibres stain of H&E?

Answer 27

pink

Question 28

What cell produces elastin fibres?

Answer 28

fibroblasts

Question 29

Can elastin fibres be branched?

Answer 29

yes

Question 30

What type of adipose tissue has large cells with a single fat globule in each cell?

Answer 30

white adipose tissue

Question 31

What colour does the fat globule usually appear on slides?

Answer 31

white

Question 32

How does brown adipose tissue differ to white adipose tissue?

Answer 32

cells have multiple fat globules instead of one per cell

Question 33

At what stage of life do we have lots of brown adipose tissue?

Answer 33

as newborns

Question 34

What is the name for mature cartilage cells?

Answer 34

chondrocytes

Question 35

What is the name for immature cartilage cells?

Answer 35

chondroblasts

Question 36

what connective tissue is avascular?

Answer 36

cartilage

Question 37

What type of cartlage is found in synovial joints?

Answer 37

hyaline cartilage

Question 38

What type of cartilage is found in the epiglottis?

Answer 38

elastic cartilage

Question 39

What type of cartilage is found in the pinna?

Answer 39

elastic cartilage

Question 40

What type of cartilage is found at the pubic symphysis?

Answer 40

fibrocartilage

Question 41

How many layers of synovial cells will you find lining the inside of the joint capsule?

Answer 41

1-4

Question 42

What are the two types of synovial cell called?

Answer 42

type A and type B

Question 43

Which type of synovial cell plays a phagocytic role?

Answer 43

type A

Question 44

What is the function of type b synovial cells?

Answer 44

produce synovial fluid

Question 45

Which type of endoplasmic reticulum are type B cells rich in?

Answer 45

rough ER

Question 46

What type of muscle would you find in the walls of arteries, the wall of the intestine and the airways of the lungs?

Answer 46

smooth muscle

Question 47

What type of muscle is the diaphagm?

Answer 47

skeletal

Question 48

Where would you expect to find myofibroblasts and myoepithelial cells?

Answer 48

ducts

Question 49

Describe the shape of the cells in smooth muscle?

Answer 49

fusiform

Question 50

If a muscle does not have striations, what type of muscle is it?

Answer 50

smooth muscle

Question 51

If a muscle has striations, what type of muscle could it be?

Answer 51

cardiac/skeletal

Question 52

Where do you find the nucleus in cardiac myocytes?

Answer 52

central

Question 53

Describe the positions of the nucleus in smooth muscle cells?

Answer 53

central

Question 54

Which type of muscle has nuceli on the edge of the cell?

Answer 54

skeletal muscle