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Histology of connective tissues Flashcards

1
Q

What colour do collagen fibres stain?

A

pink

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2
Q

What type of connective tissue has…
Widely spaced collagen fibres
Fibroblasts/fibrocytes
unstained ground substance

A

Loose connective tissue

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3
Q

What cells can connective tissue cells be derived from?

A

mesenchymal cells

haematopoeitic stem cells

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4
Q

Osteoblasts are derived from which cell?

A

mesenchymal cells

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5
Q

Chondrocytes are derived from which cell?

A

mesenchymal cells

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6
Q

Collagen, elastin and reticulin are all examples of what type of fibre?

A

Visible fibres

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7
Q

What part of connective tissue does not stain with H&E?

A

ground substance

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8
Q

What comprises ground substance?

A

proteoglycans
glycosaminoglycans
invisible fibres

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9
Q

laminin and fibronectin are examples of what type of fibre?

A

invisible fibres

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10
Q

What are the 4 types of connective tissue?

A

loose fibrous
dense fibrous
hard
fatty

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11
Q

What type of connective tissue is cartilage?

A

hard connective tissue

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12
Q

What do fibroblasts secrete that forms collagen?

A

tropocollagen subunits

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13
Q

Where is collagen assembled?

A

extracellularly

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14
Q

Describe tropocollagen

A

triple helix of peptides

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15
Q

What type of collagen is in the skin?

A

type 1

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16
Q

What type of collagen is in the cartilage?

A

type 2

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17
Q

Type 1 collagen is found in which part of the body?

A

the skin

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18
Q

Type 2 collagen is found in which part of the body?

A

catilage

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19
Q

What type of collagen is reticulin and where is it found?

A

reticulin is type 3 collagen

reticulin is found in the liver, spleeen and bone marrow

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20
Q

what type of collagen is present in basement membranes?

A

type IV

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21
Q

In which part of the body would you find type V collagen?

A

placenta

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22
Q

Describe what the difference between loose and dense connective tissue is?

A

In loose connective tissue- widely spaced thin collagen fibres
In dense connective tissue- closely spaced thick collagen fibres

23
Q

What subtypes of dense connective tissue are there?

A

irregular dense connective tissue

regular dense connective tissue

24
Q

What is the difference between regular and irregular dense connective tissues?

A

regular- regularly arranged collagen fibres

irregular- haphazardly arranged collagen fibres

25
Q

Why does reticulin require a silver stain?

A

It is not visible on H&E

26
Q

What does reticulin form in many organs?

A

A supporting scaffold

27
Q

What colour do elastin fibres stain of H&E?

28
Q

What cell produces elastin fibres?

A

fibroblasts

29
Q

Can elastin fibres be branched?

30
Q

What type of adipose tissue has large cells with a single fat globule in each cell?

A

white adipose tissue

31
Q

What colour does the fat globule usually appear on slides?

32
Q

How does brown adipose tissue differ to white adipose tissue?

A

cells have multiple fat globules instead of one per cell

33
Q

At what stage of life do we have lots of brown adipose tissue?

A

as newborns

34
Q

What is the name for mature cartilage cells?

A

chondrocytes

35
Q

What is the name for immature cartilage cells?

A

chondroblasts

36
Q

what connective tissue is avascular?

37
Q

What type of cartlage is found in synovial joints?

A

hyaline cartilage

38
Q

What type of cartilage is found in the epiglottis?

A

elastic cartilage

39
Q

What type of cartilage is found in the pinna?

A

elastic cartilage

40
Q

What type of cartilage is found at the pubic symphysis?

A

fibrocartilage

41
Q

How many layers of synovial cells will you find lining the inside of the joint capsule?

42
Q

What are the two types of synovial cell called?

A

type A and type B

43
Q

Which type of synovial cell plays a phagocytic role?

44
Q

What is the function of type b synovial cells?

A

produce synovial fluid

45
Q

Which type of endoplasmic reticulum are type B cells rich in?

46
Q

What type of muscle would you find in the walls of arteries, the wall of the intestine and the airways of the lungs?

A

smooth muscle

47
Q

What type of muscle is the diaphagm?

48
Q

Where would you expect to find myofibroblasts and myoepithelial cells?

49
Q

Describe the shape of the cells in smooth muscle?

50
Q

If a muscle does not have striations, what type of muscle is it?

A

smooth muscle

51
Q

If a muscle has striations, what type of muscle could it be?

A

cardiac/skeletal

52
Q

Where do you find the nucleus in cardiac myocytes?

53
Q

Describe the positions of the nucleus in smooth muscle cells?

54
Q

Which type of muscle has nuceli on the edge of the cell?

A

skeletal muscle

IMMS (5 decks)

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