Histology of CNS Flashcards

1
Q

Afferent signals

A

Signals passing to the CNS

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2
Q

Efferent signals

A

Signals passing away from the CNS

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3
Q

Principal cell types on Nervous tissue

A
Astrocytes (CNS)
Microglia (CNS)
Oligodendrocytes(CNS)
Ependymal cells (CNS)
Schwann cells (PNS)
Capsular cells (PNS)
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4
Q

Type of transport by which viruses are transported into the CNS

A

Retrograde transport by Dynein

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5
Q

Types of Neurons

Based on shape

A

Multipolar
Bipolar
Pseudo unipolar

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6
Q

Types of neurons based on projections

A

Sensory neurons
Interneurons
Motor neurons

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7
Q

Examples of Multipolar neurons

A

Purkinje cells, pyramidal cells, interneurons

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8
Q

Examples of Bipolar neurons

A

olfactory, retinal cells

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9
Q

Examples of Pseudounipolar

A

sensory neurons

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10
Q

Neurolemma

A

The outer most layer of the Schwann cell lamellae

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11
Q

Most numerous cells in CNS

A

Astrocytes

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12
Q

Characteristics of Astrocytes

A

Astrocytes form the Blood Brain Barrier with the help of the endothelial cells connected by tight junctions
Astrocytes are highly susceptible to the formation of neoplasms
Play a major role in electrolyte balance
Produce neurotrophic factors necessary for neuronal survival

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13
Q

Produce nerve growth factors

A

Oligodendrocytes

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14
Q

Layers of cerebrum

A
Molecular layer
Outer granular layer
Outer pyramidal layer
Inner granular layer
Inner pyramidal layer 
Polymorphic layer
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15
Q

Layers of cerebellum

A

Molecular layer Purkinje layer

Granular layer

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16
Q

What makes up the blood brain barrier?

A

Endothelium, Basement membrane, astrocytes

17
Q

What makes up the CSF barrier?

A

Endothelium, basement membrane and choroid cells

18
Q

Sites of proteins synthesis in neurons

A

Nissl Substances

19
Q

Components of a neuronal cytoskeleton

A

Neurofilament, microfilament and microtubule

20
Q

Which part of the cell body lacks Nissl substance?

A

Axon hillock

21
Q

Provide structural support for the neuron, and are

most numerous in the axon and the proximal parts of dendrites

A

Neurofilaments

22
Q

Form a matrix near the periphery of the neuron

A

Microfilaments

23
Q

Are found in all parts of the neuron, and are the cytoplasmic
organelles used in axonal transport

A

Microtubules

24
Q

Taper from the cell body and provide the major surface for synaptic
contacts with axons of other neurons

25
Has a uniform diameter and may branch at right angles into | collaterals along the length of the axon
Axon
26
Adjacent to the axon hillock, contains numerous voltage-sensitive sodium ion channels and where conduction of electrical activity as an action potential is initiated
The initial segment
27
Transported to synaptic terminals by slow anterograde transport
Cytoskeletal | proteins, enzymes, and precursors of small molecule neurotransmitters
28
Unlike neurons, they readily divide and proliferate
Glial /Supporting Cells
29
The most numerous glial cells in the CNS
Astrocytes
30
Precursors of astrocytes
Radial glia
31
Derived from bone marrow monocytes and enter the CNS after birth
Microglia cells
32
The supporting cells of the peripheral nervous system (PNS)
Schwann cells