Histology of cartilage Flashcards

1
Q

What are the four basic tissues in the human body?

A

A: Epithelium, Connective tissue, Muscle tissue, Nerve tissue.

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2
Q

What is the primary role of connective tissue?

A

To support the other three basic tissues of the body.

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3
Q

What are the types of connective tissue?

A

Loose or Dense; Dense can be regular or irregular.

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4
Q

What are the main constituents of cartilage?

A

Cells, Ground substance (matrix), and Fibers.

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5
Q

What are the roles of cartilage in the body?

A

Provides smooth articular surfaces, acts as a shock absorber, offers structural support, and aids in new bone formation.

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6
Q

What type of collagen is predominant in hyaline cartilage?

A

Type II collagen fibrils.

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7
Q

What is the significance of the high water content in the cartilage matrix?

A

It is essential for the resilience of the cartilage.

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8
Q

How does cartilage receive nourishment?

A

By diffusion through the water in the ground substance, as cartilage is avascular.

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9
Q

Where is hyaline cartilage found in the body?

A

Articular ends of bones, costal cartilage, trachea, bronchi, larynx, epiphyseal growth plate, nasal septum, and fetal skeleton.

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10
Q

What is the function of the perichondrium in cartilage?

A

It surrounds hyaline cartilage, providing a source of new cartilage cells, except at the articular ends of joints, sites of bone formation, nasal, and costal cartilages.

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11
Q

What is the difference between appositional and interstitial growth in cartilage?

A

Appositional growth adds new cartilage on the surface, increasing diameter, while interstitial growth occurs within existing cartilage, increasing length.

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12
Q

Why is the repair of cartilage poor?

A

Due to the avascularity of cartilage, immobility of chondrocytes, and the limited ability of mature chondrocytes to proliferate.

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13
Q

What clinical condition is associated with damage to articular cartilage?

A

Osteoarthritis

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14
Q

What are the locations where elastic cartilage is found?

A

External ear (pinna), external auditory canal, Eustachian tube, epiglottis, apex of arytenoid cartilage, corniculate, and cuneiform cartilages.

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15
Q

What type of collagen is abundant in fibrocartilage?

A

Type I collagen, with some Type II collagen.

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16
Q

Describe the origin of chondrocytes

A
17
Q

______ in the matrix accounts for its weight bearing capacity

A

Hyaluronic acid