Histology (kinda but not really)

Question 1

Hyperkeratosis

Answer 1

increased thickness of keratin layer

Question 2

parakeratosis

Answer 2

persistence of nuclei in the keratin layer

Question 3

acanthosis

Answer 3

increased thickness of epidermis

Question 4

papillomatosis

Answer 4

irregular epithelial thickening

Question 5

Spongiosis

Answer 5

oedema in the epidermis between the keratinocytes - increased prominence of intercellular prickles

Question 6

4 main reaction patterns in inflammatory skin disease

Answer 6

1. Spongiotic-intraepidermal oedema e.g. eczema
2. Psoriasiform-elongation of the rete rigges e.g. psoriasis
3. Lichenoid-basal layer damage e.g. lichen planus and lupus
4. Vesiculobullous-blistering e.g. pemphigoid, pemphigus and dermatitis herpetiformis