Histology: Heart and Vessels Flashcards
arteries
blood away from heart
veins
blood toward heart
exchange at capillaries?
nutrient, oxygen, waste
capillary structure?
singe layer of simple squamous epithelium surrounded by basement membrane
endothelium
the simple squamous epithelium lining vessels
vessels?
all lined by epithelium
red blood cell diameters?
7.5 microns
vessel is 8 microns (barely fits!)
passive exchange
simple diffusion to capillaries
-small molecules (water-soluble) and water
pinocytotic exchange
transport soluble high molecular weight molecules across endothelial wall
invaginations of cell membrane on both inner and outer surfaces
diapedesis
ameboid migration movement that allows cells (WBCs and macrophages) to pass endothelium
also done by immune cells
capillary junctions
adjacent cell membranes joined by tight junctions
prevent fluid loss
-not a strong adhesion
white blood cells can break these tight junctions
red blood cells
can bend (flexible)
fenestrae
in some organ capillary endothelium
thin windows
-pores closed by diaphragm thinner than unit membrane
discontinuous capillary
sinusoid
pericytes
cells surrounding capillaries and small venules
supportive - angiogenesis and vessel repair
may have contractile properties
-possible cause for constriction of vessels
sinusoid
not continuous membrane (or basement membrane)
where you need an excessive amount of exchange
liver, spleen, bone marrow
disse space
in liver
-allows direct communication between vascular space and parenchyma of organ
things can move back and forth
phagocytic cells
in some sinusoids
-
kupffer cells
liver sinusoids