Histology

Question 1

What makes up the renal lobule?

Answer 1

Pars convoluta + pars radiata

Question 2

Tubules in the pars convoluta

Answer 2

1. PCT
2. DCT
3. (collecting duct)

Question 3

Tubules in the pars radiata

Answer 3

1. Descending thick limb
2. Ascending thick limb
3. Collecting duct

Question 4

EM to LM correlation for PCT and descending thick limb

• size
• microvilli
• mitochondria
• basolateral infoldings

Answer 4

EM -> LM
-large cells -> nuclei spread out

• numerous microvilli -> fuzzy apical surface obstructing lumen
• Numerous mitochondria -> eosinophilic cytoplasm
• Numerous basolateral infoldings -> borders b/w cells not apparent

Question 5

EM to LM correlation for DCT and ascending thick limbs

• size
• microvilli
• mitochondria
• basolateral infoldings

Answer 5

EM -> LM
-small cells -> nuclei close together

• few microvilli -> sharp apical surface wide lumen
• numerous mitochondria -> eosinophilic cytoplasm
• Numerous basolateral infoldings -> borders b/w cells not apparent

Question 6

EM to LM correlation for collecting duct

• size
• microvilli
• mitochondria
• basolateral infoldings

Answer 6

EM -> LM
-small cells -> nuclei close together

• few microvilli -> sharp apical surface wide lumen
• few mitochondria -> pale cytoplasm
• few basolateral infoldings -> borders b/w cells visible

Question 7

List 3 tubules in the deep medulla

Answer 7

1. Thin limbs of loop of henle
2. Collecting ducts
3. Vasa recta

Question 8

Both thin limbs of LD and vasa recta have which epithelium? how can you tell the 2 apart?

Answer 8

Simple squamous

• thicker in thin limbs
• vasa recta may have RBCs