Histology Flashcards

1
Q

The vagina is made up of what kind of epithelium?

A

stratified squamous epithelium
non-keratinized

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2
Q

the cervix is made up of what kind of epithelium?

A

columnar epithelium

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3
Q

what part of the cervix is the most susceptible to malignancy?

A

transitional zone

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4
Q

the uterine portion of the cervix contains what type of epithelium?

A

tall columnar mucus-secreting epithelium

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5
Q

Describe the histologic features of the endocervical mucosa.

A

simple columnar epithelium on a thick lamina propria
contains the plica palmata (folded mucosa)

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6
Q

the muscular layer of the vagina is continuous w/ what uterine structure

A

the myometrium

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7
Q

the perimetrium consists of what?

A

serosa adventitia made up of loose connective tissue

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8
Q

the uterine wall is of what type of epithelium?

A

columnar epithelium

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9
Q

blood vessels can be found within which layer of the uterine wall

A

basalis layer

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10
Q

what happens to the uterine wall during the secretory stage

A

functionalis and basalis layers thicken

glands enlarge and become tortuous

secretory products increase

fibroblasts of the stroma accumulate glycogen and fat

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11
Q

what distinct histologic characteristic can be observed when the endometrium is in its secretory stage

A

glands take on a “saw tooth” appearance

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12
Q

what happens to the basalis layer of the endometrium during the menstrual phase

A

remains mostly unaffected

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13
Q

what happens to the functionalis layer of the endometrium during the menstrual phase

A

becomes desquamated

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14
Q

the fallopian tubes are divided into these 4 sections.

A

infundibulum
ampulla
Isthmus
Intramural portion

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15
Q

list the contents of the infundibulum of the fallopian tubes.

A

fimbriae
branching finger-like projections of connective tissue
lined by ciliated epithelial cells

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16
Q

what is the primary function of the fimbriae?

A

conduct spermatozoa upward and ova downward towards the endometrial cavity

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17
Q

in what region of the fallopian tubes does fertilization occur?

A

ampulla

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18
Q

list the contents of the ampulla region of the fallopian tubes?

A

interwoven circular & longitudinal layers of smooth muscle

folded mucosa

simple columnar epithelium on lamina propria

ciliated cells interspersed w/ secretory Peg cells

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19
Q

List the contents of the serosa layer of the isthmus region of the fallopian tube

A

Serosa-visceral peritoneum w/ mesothelium covered by squamous epithelium & loose connective tissue

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20
Q

Describe the histological features of the isthmus mucosal layer of the fallopian tubes

A

contains tall fold and simple columnar ciliated cells

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21
Q

compared to the other regions of the fallopian tubes, what is different about the intramural part?

A

number of ciliated cells decreases

lumen narrows

proportion of SM increases

22
Q

what type of epithelium makes up the ovaries?

A

simple cuboidal

23
Q

what region of the ovaries contain oocytes

24
Q

the medulla of the ovary consists of what?

A

LCT and blood vessels

25
what is the overlying layer of dense CT that covers the ovaries called?
tunica albuginea
26
the primordial follicle forms during which phase of life?
fetal development
27
what changes in the primordial follicle occur with onset of puberty
oocytes increase in size (NOT number) formation of zona pellucida now called a primary follicle
28
stomal cells of the secondary follicles will differentiate into what?
inner and outer theca
29
what is the purpose of the theca?
secretes steroids and provides nutrients for the developing follicle
30
what are atertic follicles
degenerative non-maturing follicles
31
what is the Tertiary follicle also called?
Graafian
32
T or F: follicular cells become cuboidal in shape as they mature.
true
33
during the early stages of primary follicles, simple cuboidal epithelium surrounds the growing oocyte. what happens in the later stages?
follicular cells undergo mitosis to become stratum granulosa and zona pellucida
34
within what layer of the follicle does the antrum develope
withing the granulosa layer
35
The Theca Interna consists of what type of cells
steroid-secreting cuboidal cells
36
the theca externa consists of what type of cells?
covering fibroblasts
37
secondary follicles transform into what type of epithelium
stratified follicular epithelium produced by granulosa cells
38
T or F: the zona pellucida express large numbers of FSH receptors
false they contain LH receptors only not sensitive to FSH
39
what layer surrounds the ZP?
corona radiate
40
what is the mound of granulosa cells surrounding the oocyte that remain w/ it until ovulation?
cumulus oophorus
41
what happens to the theca interna once it loses the oocyte
differentiates into theca lutein cells to become the corpus hemorrhagicum (CH)
42
the CH is transformed into what?
the corpus luteum
43
T or F: Theca lutein cells respond to FSH to simulate aromatase activity
FALSE theca lutein cells respond to LH granulosa lutein cells respond to fSH
44
what doe the theca and granulosa cells produce postovulation?
granulosa cells: produce progesterone & estrogen theca cells: produce testosterone
45
what does the corpus albicans mostly consists of?
collagen and fibroblasts
46
describe the process of follicular atresia.
degeneration of oocyte and autolysis of granulosa cells clumping of nuclear chromatin to form pyknotic nuclei shrinkage and lysis of follicular cells thickening of BM and separation of GC from TI to forma a "glassy membrane"
47
Histologically, what are mammary glands?
highly modified sweat glands
48
the alveolar glands contain what?
lactiferous ducts
49
T or F: the mammary glands are abundant w/ adipose tissue when not lactating
true
50
what kind of connective tissues is seen in the mammary glands?
dense irregular interlobular CT
51
what histologic changes of the breast will occur during pregnancy
mammary glands become activated: proliferation of ducts and secretory unites decreased CT glandular alveoli along w/ excretory ducts