histology Flashcards

1
Q

types of tissues

A

epithelial, connective, muscular, nervous

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2
Q

cell junctions

A

how cells are held together to form tissues:
- tight
- adherens
- desmosomes
- hemidesmosomes
- gap

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3
Q

tight junction

A

weblike (strands of transmembrane proteins fused together). Inhibits passage of substances between cells and prevents contents of organs from getting out.

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4
Q

where are tight junctions found

A

stomach, intestines, urinary bladder

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5
Q

adherens junctions

A
  • dense layer of intracellular proteins attach to membrane proteins and microfilaments of the cytoskeleton
  • forms adhesion belts that CONTAIN PLAQUE
  • helps epithelial surfaces resist separation during contractile activities.
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6
Q

desmosomes

A
  • like buttons
  • helps with stability of cell and tissue
  • prevent separation under tension and contraction
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7
Q

where do we find desmosomes

A

outermost layer of skin (epidermis), cardiac muscle

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8
Q

hemidesmosomes

A
  • like desmosomes but do not link adjacent cells
  • anchor cells to basement membrane
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9
Q

gap junctions

A
  • plasma membrane of cells are not fused together, but have an intercellular gap
  • has connexons
  • allows for diffusion ions and small molecules to pass between cells
  • allows for cells to communicate with each other - rapid spread of nerve/muscle impulses
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10
Q

where do you find gap junctions

A

nervous system, smooth muscles of heart, GI tract, uterus

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11
Q

which junction does not allow for cellular leakage

A

tight

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12
Q

which junction attaches the cell to the basement membrane

A

hemidesmosomes

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13
Q

which junction has connexons

A

gap

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14
Q

which junction connects to the microfilaments of the cytoskeleton

A

adherens

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15
Q

what is epithelial tissue

A
  • cells arranged in continuous sheets - either a single layer or multi-layered
  • cells are closely packed together and held by junctions
  • has its own nervous supply but no blood supply (avascular)
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16
Q

structural features of epithelial tissue

A
  • apical (free) surface - top layer, has cilia or microvilli
  • lateral surfaces have junctions
  • basal surface - bottom/deepest layer. connects to basement membrane with hemidesmosomes
17
Q

basement membrane

A
  • extracellular layer that has 2 parts - 1) basal lamina (secreted by epithelium) 2) reticular lamina (closer to underlying connective tissue)
18
Q

function of basement membrane

A

anchors epithelium to underlying connective tissue

19
Q

how can we classify epithelial tissue structurally

A
  • layers - simple, pseudostratified, stratified
  • shape - squamous, cuboidal, columnar, transitional
20
Q

functions of epithelial tissue

A
  • protects
  • secretes (mucus, hormones, enzymes)
  • absorbs (GI tract)
  • excretes (urinary tract)
  • filtration (kidneys)
  • special sense organs (combines with nervous tissue)
21
Q

where do we find epithelial tissue

A
  • covering/lining surfaces. outer covering of skin and lining hollow organs
  • forms the secreting portion of glands (thyroid, sweat, adrenal, digestive)
22
Q

what is a single layer of epithelial tissue called

A

simple

23
Q

how do we refer to multiple layer of epithelial tissue

A

stratified

24
Q

which portion of the basement membrane is secreted by the epithelium

A

basal lamina

25
Q

what are the 2 types of epithelium

A

glandular (glands) and surface (outer layer of skin and hollow organs)

26
Q
A