Histology Flashcards
Sinusoids
Non true capillaries: vascular channels, much larger
discontinuous endothelium with discontinuous basement membrane
Think liver, spleen, bone marrow
allow for direct communication b/w parenchymal cells and endothelial spaces
associated with phagocytes (Kupferr cells)
Tunica Intima
deepest layer
- endothelium
- BM
- subendothelial CT
- IEL (more visible in larger vessels)
Tunica Media
- Smooth muscle
- CT fibers
- EEL
muscle organized in spiraling orientation
EEL more prominent in medium sized vessels
Largest layer in arteries
Tunica adventitia
mostly dense CT with lots of collagen from fibroblasts
Arterioles
Thin intima, no CT, no IEL
controls flow to capiliaries–> controls BP
no EEL
Medium (muscular) arteries
small amount of CT, IEL present
40 layers of smooth muscle, ANS controls blood flow. EEL present but hard to see
Large (elastic) arteries
lots of CT, limited IEL
lots of smooth muscle with high elastic fibers
elasticity allows you to decrease pulsatility of blood flow during delivery to peripheral vessels
tunica adventitia prevents over-distension of inner layers
contain vaso vasorum
Vein structure
large lumen, thinn intima and media with very small amount of elastic lamina
adventitia is thickest with lots of fibrous CT and no smooth muscle
valves made of intima +endothelium
Arteries vs. veins
Veins always have greater CSA than artery that it runs with
Arteries have more smooth muscle and more elastic fibers and IEL
veins have more collagen, less smooth muscle and valves
Endocardium
continuous with tunica intima of great vessels
- endothelium + BM
- Subendothelial CT
- Subendocardial CT (binds endocardium with myocardium)
- Purkinje fibers: impulse conducting system
Purkinje fibers
cardiac muscle made for impulse conduction
specialized myofiber with high glycogen content
Myocardium
bundled cardiac muscle fibers
thickets in ventricles
supported by thin CT networks that carry vessels and nerves
Epicardium
visceral layer of pericardial sac
fluid filled
carries nerves and ganglia
lots of adipose
heart valves
evagniations of endocardium
supported by fibrous rings
IEL
Most prominent in Medium (muscular) arteries
- may not be visible in arterioles or large (elastic) arteries