Histology Flashcards
color of adrenal cortex and why
yellowish in colour due to high content of lipid
origin of the adrenal cortex
Mesodermal in origin
Zona glomerulosa
- which gland?
- location?
- group cell morphology?
- cells and nucleus morphology?
- secrete?
- adrenal cortex
- under the capsule
- cells arranged into round and oval groups
- The cells are columnar with spherical deeply stained nuclei
- secrete aldosterone which causes sodium retention under
control by angiotensinogen II
The cells that have the highest content of cholesterol in the body.
Zona fasciculata
what secreted by Zona fasciculata?
glucocorticoids which is controlled by ACTH
composed of straight parallel cords of cells in adrenal cortex
Zona fasciculata
The broadest zone in adrenal cortex
Zona fasciculata
Zona fasciculata characteristics
- the broadest zone composed staight parallel cords of cells
- the cells are polyhedral with large vesicular nuclei which can be binucleated
- Their cytoplasm is filled with lipid droplets so appear vacuolated due to dissolved lipid droplets and has a spongy appearance, so called spongiocytes
- The cells have the highest content of cholesterol in the body
- The cells secrete glucocorticoids which is controlled by ACTH.
from adrenal cortex that secrete sex hormones
Zona reticularis
has less lipid droplets and more lipofuscin pigments
Zona reticularis
origin of adrenal medulla
ectodermal in origin
has Chromaffin cells
adrenal medulla
secrete adrenaline Chromaffin cells
Chromaffin cells
Morphology of Chromaffin cells
The cells are oval or polygonal with eccentric nuclei with basophilic cytoplasm
stain of medullary cells makes it brown
Chromaffin reaction
stain of medullary cells makes it red
Iodine stain
stain of medullary cells makes it green
Vulpian test
what to add in Vulpian test on medullary cells
ferric chloride
what to add in Chromaffin reaction test on medullary cells
potassium dichromate
origin of thyroid gland
endoderm
Parenchyma of thyroid gland consists of
thyroid follicles & inter-follicular cells
lining of the thyroid follicles
low cuboidal epithelium
what in the lumen of the thyroid follicles
colloid, a homogenous gelatinous acidophilic material stained intensely with PAS
synthesize thyroid hormones
follicular cells (thyrocytes)
cells secrete calcitonin?
parafollicular cells ( C cells)
cells secrete parathormone?
Chief cells of parathyroid glands
cells of pancreas
A cells
B cells
D cells
secretion and location of A cells of pancreas
secrete primarily glucagon and are usually located
peripherally
secretion and location of B cells of pancreas
produce insulin, are the most numerous, and are
located centrally
secretion and location of D cells of pancreas
secretion and location of B cells of pancreas