Histo: Gynae

Question 1

Endometrial Cancer

Answer 1

○ Endometrioid - perimenopausal, oestrogen sensitive, good prognosis
○ Non endometrioid - clear cell, older, bad, hobnail

Question 2

Ovarian - Epithelial

Answer 2

■ Serous - most common, psammoma bodies
■ Mucinous - mucin secreting cells
■ Endometrioid - tubular glands
■ Clear cell - hobnail

Question 3

Ovarian Germ Cell

Answer 3

teratoma, dysgerminoma, choriocarcinoma (secrete hCG)

Question 4

Ovarian Sex Cord

Answer 4

■ Granulosa-theca cells (& therefore tumours) convert androgens to oestrogen
■ Sertoli-Leydig - androgen
■ Ovarian fibroma - Meig’s syndrome (ascites + pleural effusion)