Histo: GI

Question 1

Diverticulitis

Answer 1

old, rectal bleeding, fever, LIF

Question 2

Sigmoid Volvulus

Answer 2

obstruction

Question 3

UC+Crohns

Answer 3

UC continuous, superficial, more likely to have blood

Question 4

Infective Colitis

Answer 4

• pseudomembrane, Abx in history

Question 5

Barett’s Oesophagus

Answer 5

metaplasia, columnar epithelium, goblet cells (intestinal)

Question 6

SCC of Oesophagus

Answer 6

alcohol, smoking, mid/lower oesophagus, invasion into submucosa

Question 7

CF

Answer 7

patients after lung transplant are more likely to get adenocarcinoma of colon

Question 8

MALT lymphoma

Answer 8

Pernicious anaemia, H pylori

Question 9

Chronic Gastritis

Answer 9

associated with pernicious anaemia and gastric ulcer

Question 10

Gastric Cancer

Answer 10

95% adenocarcinoma
○ Intestinal - well differentiated
○ Diffuse - poorly differentiated (linitis plastica, signet ring cell)
○ Signet ring cell - contains mucin which pushes nucleus to cell periphery

Question 11

Lower GI Cancer

Answer 11

○ Adenocarcinoma most common - male with change in bowel habit, weight loss, bleeding PR
○ AFP -> hyperplastic polyps
○ Polyps not associated with increased cancer risk -> hamartomatous