Histo: GI tract: mouth --> Rectum Flashcards
oral cavity?
startified squamous noncornified
3 salivary glands?
- parotid
- submandibular
- sublingual
salivary gland products?
- salivary amylase –> carbs
- lactoferrin and lysozymes –> antibacterial
- secretaory IgA: immune
4: HCO3-: minimizes tooth decay and neutralizes heart burn
Parotid gland
dark pink cells
H20 based
SEROUS
product: salivary amylase
Submandibular gland
mixed: MOSTLY SEROUS
serous demilunes created
serous: produce salivary amylase
mucous: produce mucins
Sublingual glands
“light pink cells” fat based
Mixed, MOSTLY MUCOUS
crown
visible portion of teeth
cervix
neck of tooth
alveolous
bony socket of tooth
enamel
made by ameoblasts before rupturing
dentin
made by odontoblasts, can be regenerated, not as hard as enamel
glands of tongue
mucous: fatty, light pink = glands of Nuhn
serous: darker pink; H2o based = von ebner’s glands
sulcus terminalis
separates anterior 2/3 from posterior 1/3
foramen cecum
deep concavity in middle of tongue
4 lingual papillae?
- Filliform: “scrapers” no taste buds
- Fungiform: “mushrooms” have taste buds
- Circumvallate: 8-12, anterior to sulcus terminalis, have taste buds.
- Foliate papillae: vertical furrows, no taste buds
ductal cells of salivary gland
reabsorb Na/Cl ; secrete K/HCO3
results in hypotonicity of saliva
4 layers of gut tube?
- Mucosa (epithelium, LP, Muscularis mucosa)
- submucosa
- muscularis externa
- adventitia/serosa
Mucosa
innermost layer
- epithelium: protective, secratory, absorptive
- LP: loose CT tissue
- muscularis mucosa: inner circular layer, outer longitudinal layer
submucosa
layer of CT w/ elastic fibers
provides mobility for mucosa
contains plexuses, nnn. PS ganglia
muscularis externa
maintains tone, propels bolus
inner circular layer, outer longitudinal layer
adventitia/serosa
outermost layer of dense CT
SEROSA = completely covered
pits/crypts
invaginations of GI tract as progresses down
evaginations = vili
goblet cells
increase in number as go down GI tract
NO GOBLET CELLS IN STOMACH
esophagus
stratified squamous, noncornified
submucosa: in star shape
cardioesophageal jn.
cardiac sphincter
change from stratified squamous to simple columnar
stomach
simple columnar
submucosa: extended into ruggae
cardiac region
surface mucous cells
undifferentiated cells
fundic region
mucous neck cells
parietal cells
zymogenic chief cells
enteroendocrine cells
pyloric region
mucous neck cells
G cells
surface mucous cells:
secrete pH neutral mucous to protect stomach epithelium
mucous neck cells
secrete acidic mucous and HCO3-
parietal cells
secrete HCl which activates pepsinogen
secrete IF
chief cells
produce enzymes pepsinogen: protein digesetion
lipase: initiates fat digestion
gastric enteroendocrine cells “ G cells”
secrete gastrin
microvilli
cytoplasmic projectsions seen throughout GI
villi
seen only in small intestine
plicae circulares
seen in SI - circular folds
none seen in ileum
3 glands of small intestine?
exocrine glands: pancreas and liver
submucosal glands: “brunner’s glands” secrete mucous; basic pH
intestinal crypts: mucosal glands
small intestine
simple columnar epithelium
- enteroendocrine cells
- paneth cells
- M cells
enteroendocrine cells
secrete GIP, somatostatin, motilin, produce hormones to stimulate cells
paneth cells
secrete lysozyme and peptide defensins to defend against bacteria
M cells
capture Ag’s and present to APs in SI
Peyer’s patches
lymph nodules where m cells are found in SI
large intestines
no villi
intestinal crypts are longer and more closely packed
simple columnar epithelium
numerous goblet cells
plica semilunares
produce sacculation of haustra b/c of longitudinal layer of tenia coli
rectum
muscularis externa incomplete
plicae transversales: 2 lt, 1 rt
rectoanal junction
where retum becomes anal canal
pectinate line
peithelium changes from endodermally derived simple columnar to ectodermally derived stratified squamous non-cornified
anal verge
becomes stratified squamous cornified
termination of anal canal