Histo Flashcards

1
Q

Major Cell Type in the respiratory system.

A

Pseduostratified Ciliated Columnar Epithelium (PCCE)

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2
Q

Olfactory cell type.

A

Bipolar Neuron

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3
Q

Function of basal cells

A

Progenitor cells

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4
Q

Function of brush cells

A

General sensation (CN V)

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5
Q

Cell type unique to the oropharynx and laryngopharynx compared to the rest of the respiratory system.

A

Non-keratinized stratified squamous epithelium (NKSSE)

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6
Q

In the larynx what type of cells line the vestibular fold and then the vocal folds?

A

Vestibular: PCCE
Vocal: NKSSE

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7
Q

In what part of the respiratory tract are ossification centers most commonly seen?

A

Trachea

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8
Q

What is the function of the granule cells in the trachea and bronchus tree?

A

Secrete catecholamines like serotonin, calcitonin, bombesin

(bombesin stimulates gastrin release from G cells to inhibit hunger. It is also used as a tumor marker for small cell lung carcinoma, gastric cancer and neuroblastoma)

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9
Q

Name the 8 division of the respiratory tree and where the hyaline cartilage stops.

A
  1. Trachea
  2. Lobar (secondary) bronchi
  3. Segmental (tertiary) bronchi

(loss of hyaline cartilage)

  1. Bronchiolus
  2. Terminal Bronchiolus
  3. Respiratory Bronchiolus
  4. Alveolar Duct
  5. Alveoli
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10
Q

Which layer of the bronchial contains the smooth muscle?

A

Mucosal Layer

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11
Q

How does the epithelium change near the termination of the respiratory tree?

A

Starts as PCCE, then simple columnar, then simple cuboidal

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12
Q

Function of Clara Cells

A

Secrete surfactant

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13
Q

What makes up the 3 layers of the air-blood barrier?

A
  1. Pneumocyte Type 1 (alveolar epithelium)
  2. Basement Membrane
  3. Capillary Endothelial Cell
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14
Q

Function of the Pneumocyte Type II cells.

A

Secrete Surfactant

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15
Q

Function of the Pores of Kohn

A

Allow ventilation between alveolar sacs if one alveolar duct becomes blocked

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16
Q

Two characteristics of alveoli that lead to symptoms in patients with emphysema.

A
  1. Decreased surface area for gas exchange

2. Increased thickness in gas exchange membrane barrier